中文名稱

Illudin S

英文名字

Illudin S

供應(yīng)商

開(kāi)曼生物

產(chǎn)品貨號(hào)

17451-1

產(chǎn)品報(bào)價(jià)

￥4034.8/1mg

產(chǎn)品說(shuō)明書(shū)

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購(gòu)買(mǎi)方式

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產(chǎn)品新聞

背景資料

Illudins are fungal sesquiterpenes that, through their unique DNA alkylating actions, have anticancer potential.{28238,28236} Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM).{28238} T-lymphocyte leukemia CEM cells that are resistant to doxorubicin (Item No. 15007), epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S.{28238} Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents.{28236,28237,28239}

產(chǎn)品描述

A cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM)

保存建議

建議您在收到開(kāi)曼生物品牌的隱陡頭菌素S (1 mg)產(chǎn)品后置于-20℃保存.

其他

開(kāi)曼生物向全球科學(xué)工作者提供多研究領(lǐng)域的生化、免疫試劑和分析試劑盒，其產(chǎn)品被廣泛應(yīng)用于腫瘤、氧化氮、神經(jīng)學(xué)、凋亡、氧化性損傷、內(nèi)分泌學(xué)等不同研究領(lǐng)域.開(kāi)曼生物可提供用于檢測(cè)的特色試劑盒，如：類(lèi)花生酸類(lèi)物質(zhì)、游離的生物標(biāo)志、環(huán)核苷、激素及氧化氮等；也提供多種高質(zhì)量試劑，包括：類(lèi)花生酸類(lèi)物質(zhì)、氧化氮試劑及許多相關(guān)脂質(zhì)、脂肪酸、酶和抗體.作為開(kāi)曼生物在中國(guó)的區(qū)域總代理，艾美捷科技有限公司將為中國(guó)客戶提供最全面的開(kāi)曼生物產(chǎn)品以及客戶訂制化服務(wù).