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  2. 多肽產(chǎn)品
  3. 多肽及其衍生物
  4. 細胞黏附肽
  5. Fibrinopeptide A, human TFA

Fibrinopeptide A, human TFA  (Synonyms: Human fibrinopeptide A TFA)

目錄號: HY-P1538A 純度: 98.78%
COA 產(chǎn)品使用指南

Fibrinopeptide A, human TFA 是由凝血酶從纖維蛋白原切割后的一種含 16 個氨基酸殘基的短肽，位于 Aα 鏈的 NH2-末端。

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Custom Peptide Synthesis

Fibrinopeptide A, human TFA Chemical Structure

Fibrinopeptide A, human TFA Chemical Structure

CAS No. : 61533-47-9

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥800
In-stock
5 mg ￥2000
In-stock
10 mg ￥3000
In-stock
50 mg   詢價  
100 mg   詢價  

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Other Forms of Fibrinopeptide A, human TFA:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Fibrinopeptide A, human TFA is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain[1].

體外研究
(In Vitro)

The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to the central region of fibrinogen and catalyzes cleavage of the 2 short peptides, the 16-residue fibrinopeptide A (FpA) and the 14-residue fibrinopeptide B (FpB), located at the NH2-termini of the Aα and Bβ chains, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
體內(nèi)研究
(In Vivo)

Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1764.60

Formula

C63H97N19O26.2C2HF3O2
CAS 號
性狀

固體

顏色

White to off-white

Sequence

Ala-Asp-Ser-Gly-Glu-Gly-Asp-Phe-Leu-Ala-Glu-Gly-Gly-Gly-Val-Arg
Sequence Shortening

ADSGEGDFLAEGGGVR
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
細胞實驗： 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
純度 & 產(chǎn)品資料
參考文獻

Fibrinopeptide A, human TFA 相關(guān)分類

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Fibrinopeptide A, human TFA
目錄號：
HY-P1538A
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