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  2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Strictosidinic acid

Strictosidinic acid 是一種具有口服活性的，從 Psychotria myriantha 葉中分離的糖苷吲哚單萜生物堿，抑制 5-HT 生物合成的前體酶并降低 5-HT 含量。Strictosidinic acid 在小鼠中具有外周緩解疼痛和解熱活性。

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Strictosidinic acid Chemical Structure

Strictosidinic acid Chemical Structure

CAS No. : 150148-81-5

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規(guī)格 價格 是否有貨
1 mg ￥5000
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  • 生物活性

  • 純度 & 產品資料

  • 參考文獻

生物活性

Strictosidinic acid, an orally active glycoside indole monoterpene alkaloid isolated from Psychotria myriantha leaves, inhibits precursor enzymes of 5-HT biosynthesis and reduces the 5-HT levels. Strictosidinic acid has peripheral analgesic and antipyretic activities in mice[1][2].

IC50 & Target

5-HT Receptor

 

體內研究
(In Vivo)

Strictosidinic acid (20 μg/μl; intra-hippocampal injection) causes a significance of 83.5% reduction in 5-HT levels. Strictosidinic acid (10 mg/kg; i.p.) causes a 63.4% reduction in 5-HT levels and a 67.4% reduction in DOPAC values in male Wistar rats, weighing 200-250 g[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

516.54

Formula

C26H32N2O9
CAS 號
性狀

固體

顏色

Light yellow to yellow

結構分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

純度 & 產品資料
參考文獻

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產品名稱：
Strictosidinic acid
目錄號：
HY-N7514
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