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  1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Isotetrandrine

Isotetrandrine 是 Stephania tetrandra 中的活性成分。

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Isotetrandrine Chemical Structure

Isotetrandrine Chemical Structure

CAS No. : 477-57-6

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1 mg ¥2476
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MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Isotetrandrine is a bioactive component in Stephania tetrandra[1].

IC50 & Target

Human Endogenous Metabolite

 

細胞效力
(Cellular Effect)
Cell Line Type Value Description References
A-431 ED50
8.4 μg/mL
Compound: 4
Cytotoxicity against human A431 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human A431 cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
HT-1080 ED50
11 μg/mL
Compound: 4
Cytotoxicity against human HT1080 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human HT1080 cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
KB ED50
10600 nM
Compound: 18
Cytotoxicity against human KB cells after 72 hrs by SRB assay
Cytotoxicity against human KB cells after 72 hrs by SRB assay
[PMID: 9917283]
KB ED50
6.6 μg/mL
Compound: 4
Cytotoxicity against human KB cells after 3 days by sulforhodamine B assay
Cytotoxicity against human KB cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
KB-V1 ED50
1.5 μg/mL
Compound: 4
Cytotoxicity against human KBV1 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human KBV1 cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
LNCaP ED50
9.4 μg/mL
Compound: 4
Cytotoxicity against human LNCAP cells after 3 days by sulforhodamine B assay
Cytotoxicity against human LNCAP cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
P388 ED50
5.6 μg/mL
Compound: 4
Cytotoxicity against mouse P388 cells after 2 days by sulforhodamine B assay
Cytotoxicity against mouse P388 cells after 2 days by sulforhodamine B assay
[PMID: 8450319]
SK-MEL-2 ED50
19.5 μg/mL
Compound: 4
Cytotoxicity against human SK-MEL-2 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human SK-MEL-2 cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
ZR-75-1 ED50
5 μg/mL
Compound: 4
Cytotoxicity against human ZR-75-1 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human ZR-75-1 cells after 3 days by sulforhodamine B assay
[PMID: 8450319]
體外研究
(In Vitro)

Fangchi, derived from the rhizoma of S. acutum and the radix of S. tetrandra and S. acutum, has been widely used for the treatment of rheumatic arthritis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

622.75

Formula

C38H42N2O6

CAS 號
性狀

固體

顏色

White to light yellow

結(jié)構(gòu)分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

純度 & 產(chǎn)品資料

純度: ≥97.0%

參考文獻
  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

產(chǎn)品名稱:
Isotetrandrine
目錄號:
HY-N6045
需求量: