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  2. Anti-infection Immunology/Inflammation GPCR/G Protein Neuronal Signaling
  3. Dengue virus Flavivirus Fungal Bacterial Histamine Receptor
  4. Nimbin

Nimbin  (Synonyms: 寧賓)

目錄號: HY-N3187 純度: ≥98.0%
COA 產(chǎn)品使用指南

Nimbin 是一種從 Azadirachta 中分離的中間體檸檬苦素，可防止 tau 聚集并增加細胞活力。Nimbin 有效抑制登革病毒 (dengue virus) 的包膜蛋白。Nimbin 具有抗炎，解熱，抗真菌，抗組胺，防腐，抗氧化劑，抗癌和抗病毒特性，并可以穿越血腦屏障。

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Nimbin Chemical Structure

Nimbin Chemical Structure

CAS No. : 5945-86-8

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥3200
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查看 Histamine Receptor 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Nimbin is a intermediate limonoid isolated from Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier[1][2][3].

細胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 20 μM
Compound: 25
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21381696]
AZ-521 cell line IC50
> 20 μM
Compound: 25
Cytotoxicity against human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21381696]
SK-BR-3 IC50
> 20 μM
Compound: 25
Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21381696]
分子量

540.60

Formula

C30H36O9
CAS 號
性狀

固體

顏色

White to off-white

中文名稱

寧賓
結(jié)構(gòu)分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: ≥98.0%

參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Nimbin
目錄號：
HY-N3187
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