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  1. GPCR/G Protein Neuronal Signaling
  2. Neuropeptide Y Receptor
  3. Neuropeptide Y (13-36), amide, human

Neuropeptide Y (13-36), amide, human  (Synonyms: Neuropeptide Y (13-36), human)

目錄號: HY-P1480 純度: 98.48%
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Neuropeptide Y (13-36), amide, human 是選擇性的神經(jīng)肽 Y2 受體 (neuropeptide Y2 receptor) 的激動劑。

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Neuropeptide Y (13-36), amide, human Chemical Structure

Neuropeptide Y (13-36), amide, human Chemical Structure

CAS No. : 122341-40-6

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查看 Neuropeptide Y Receptor 亞型特異性產(chǎn)品:

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生物活性

Neuropeptide Y (13-36), amide, human is a selective?neuropeptide Y2 receptor?agonist[1].

IC50 & Target[2]

NPY Y2 receptor

 

體內(nèi)研究
(In Vivo)

Neuropeptide Y (13-36) (intraventricular injection; 25-3000 pmol) produces a dose-dependent increase (up to 14%; ED50 value of 0.3 nmol for overall effects and 0.97 nmol for the peak effects) in mean arterial blood pressure in the awake, unrestrained male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat[1].
Neuropeptide Y (13-36) (intracerebroventricular injection; 50 ng; alone; injected 30 and 15 min before measurements) injected into na?ve mice impairs social novelty preference, but not sociability, and this effect is inhibited by the NPY Y2 receptor antagonist BIIE 0246[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male ICR mice (age 4-7 weeks)[2]
Dosage: 50 ng/mouse
Administration: Intracerebroventricular injection
Result: Significantly decreased interaction time with the new stranger mouse in session 3 that NPY 13-36.
分子量

3000.40

Formula

C134H207N41O36S

CAS 號
性狀

固體

顏色

White to off-white

Sequence

Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2

Sequence Shortening

PAEDMARYYSALRHYINLITRQRY-NH2

運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

純度 & 產(chǎn)品資料
參考文獻
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱:
Neuropeptide Y (13-36), amide, human
目錄號:
HY-P1480
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