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  3. 7-Hydroxycoumarin-4-acetic acid

7-Hydroxycoumarin-4-acetic acid 是一種 pH 指示染料,與牛血清白蛋白 (BSA) 在反應(yīng)氨基的位置共價結(jié)合 (λmax=326 nm)。

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7-Hydroxycoumarin-4-acetic acid Chemical Structure

7-Hydroxycoumarin-4-acetic acid Chemical Structure

CAS No. : 6950-82-9

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  • 生物活性

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生物活性

7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm)[1].

細(xì)胞效力
(Cellular Effect)
Cell Line Type Value Description References
B16-F10 IC50
> 10 μM
Compound: HCAA
Cytotoxicity against mouse B16-F10 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Cytotoxicity against mouse B16-F10 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 33956447]
HepG2 IC50
> 10 μM
Compound: HCAA
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 33956447]
HT-29 IC50
> 10 μM
Compound: HCAA
Cytotoxicity against human HT-29 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
[PMID: 33956447]
分子量

220.18

Formula

C11H8O5

CAS 號
性狀

固體

顏色

White to off-white

Emission (Em)

450

Excitation (Ex)

415

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

純度 & 產(chǎn)品資料
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產(chǎn)品名稱:
7-Hydroxycoumarin-4-acetic acid
目錄號:
HY-D0112
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