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  2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. MCC

MCC 是一種不可降解的 (non-cleavable) ADC 連接子，可用于合成 ADC，如 MCC-DM1。

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MCC Chemical Structure

MCC Chemical Structure

CAS No. : 104676-09-7

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規(guī)格 價格 是否有貨 數(shù)量
5 mg ￥350
In-stock
10 mg ￥600
In-stock
25 mg ￥1250
In-stock
50 mg ￥2100
In-stock
100 mg ￥3400
In-stock
200 mg   詢價  
500 mg   詢價  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].

體外研究
(In Vitro)

Antibody-drug conjugates (ADCs) are potent cytotoxic drugs linked to antibodies through chemical linkers, and allow specific targeting of drugs to neoplastic cells. Anti-CD22-MCC-DM1 is broadly effective in vitro against multiple NHL cell lines[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

236.27

Formula

C12H16N2O3
CAS 號
性狀

固體

顏色

Light yellow to brown

運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

純度 & 產(chǎn)品資料
參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
MCC
目錄號：
HY-132251
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