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  1. Metabolic Enzyme/Protease Neuronal Signaling Membrane Transporter/Ion Channel
  2. FAAH TRP Channel
  3. N-Arachidonoylserotonin

N-Arachidonoylserotonin  (Synonyms: Arachidonyl serotonin; AA-5-HT)

目錄號(hào): HY-103337 純度: ≥98.0%
COA 產(chǎn)品使用指南

N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) 是一種有效的脂肪酰胺水解酶 (FAAH) 抑制劑,IC50 為 1~12 μM。N-Arachidonoylserotonin 還可作為瞬時(shí)受體電位香草型 1 (TRPV1) 通道的拮抗劑 (IC50=70~100 nM)。N-Arachidonoylserotonin 對(duì)嚙齒動(dòng)物有鎮(zhèn)痛作用。

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N-Arachidonoylserotonin Chemical Structure

N-Arachidonoylserotonin Chemical Structure

CAS No. : 187947-37-1

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規(guī)格 價(jià)格 是否有貨 數(shù)量
5 mg (108.07 mM * 0.1 mL in methyl acetate) ¥1150
In-stock
10 mg (108.07 mM * 0.2 mL in methyl acetate) ¥1900
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25 mg (108.07 mM * 0.5 mL in methyl acetate) ¥3900
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50 mg (108.07 mM * 1 mL in methyl acetate) ¥6000
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查看 TRP Channel 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 μM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC50=70~100 nM). N-Arachidonoylserotonin is analgesic in rodents [1].

IC50 & Target

IC50: 1~12 μM (FAAH), 70~100 nM (TRPV1 channels)[1]

分子量

462.67

Formula

C30H42N2O2

CAS 號(hào)
性狀

液體

顏色

Colorless to light yellow

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式

Solution, -20°C, 2 years

純度 & 產(chǎn)品資料

純度: ≥98.0%

參考文獻(xiàn)
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產(chǎn)品名稱:
N-Arachidonoylserotonin
目錄號(hào):
HY-103337
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