Ademetionine

別名: AdoMet, S-Adenosylmethionine, SAMe 中文名稱：腺苷蛋氨酸

此產(chǎn)品容易吸水受潮，請(qǐng)密封保存。

目錄號(hào)：S5109 Purity: 99.09%

Ademetionine (AdoMet, S-Adenosylmethionine, SAMe), also known as SAMe, is a specific form of the amino acid methionine known as S-adenosyl-methionine. It is essential for the formation of glutathione, a water-soluble peptide that helps the body fight free radicals.

Ademetionine Chemical Structure

CAS: 29908-03-0

規(guī)格	價(jià)格	庫(kù)存
10mM (1mL in DMSO)	810.81	現(xiàn)貨
25mg	795.08	現(xiàn)貨
1g	7944.3	現(xiàn)貨
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產(chǎn)品質(zhì)控

批次：純度： 99.09%

99.09

Ademetionine相關(guān)產(chǎn)品

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相關(guān)化合物庫(kù)	FDA藥物庫(kù) 天然產(chǎn)物庫(kù) 已知活性藥物庫(kù)-I 多樣性化合物母核庫(kù)	點(diǎn)擊展開

生物活性

產(chǎn)品描述	Ademetionine (AdoMet, S-Adenosylmethionine, SAMe), also known as SAMe, is a specific form of the amino acid methionine known as S-adenosyl-methionine. It is essential for the formation of glutathione, a water-soluble peptide that helps the body fight free radicals.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
臨床試驗(yàn)信息 (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05312372	Withdrawn	Esophageal Squamous Cell Carcinoma	Institut de Recherches Internationales Servier\|ADIR a Servier Group company\|Servier	May 2025	Phase 1\|Phase 2
NCT05775718	Recruiting	Bone Marrow Transplant\|Stem Cell Transplant	University of Colorado Denver\|GlaxoSmithKline	December 1 2024	Phase 2
NCT05279196	Not yet recruiting	Muscle Injury	University Hospital Montpellier	September 2024	Not Applicable
NCT06309173	Not yet recruiting	Multiple Sclerosis	University Hospital Basel Switzerland	September 2024	--
NCT06251999	Not yet recruiting	Elderly Patients	Shanghai 6th People''s Hospital	August 1 2024	Phase 4
NCT06280742	Not yet recruiting	Multiple Sclerosis	Assistance Publique - H?pitaux de Paris	July 1 2024	Not Applicable

參考文獻(xiàn)
[1] Bottiglieri T. Expert Opin Investig Drugs. 1997, 6(4):417-26.

參考文獻(xiàn)

[1] Bottiglieri T. Expert Opin Investig Drugs. 1997, 6(4):417-26.

化學(xué)信息&溶解度

分子量	398.44	分子式	C₁₅H₂₂N₆O₅S
CAS號(hào)	29908-03-0	SDF	Download Ademetionine SDF
Smiles	C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
儲(chǔ)存條件(自收到貨起)	3年 -20°C 粉末（密封）	儲(chǔ)備液保存和期限建議分裝儲(chǔ)備液，避免反復(fù)凍融！	1年-80°C溶于溶劑
儲(chǔ)存條件(自收到貨起)	3年 -20°C 粉末（密封）	儲(chǔ)備液保存和期限建議分裝儲(chǔ)備液，避免反復(fù)凍融！	1個(gè)月-20°C溶于溶劑

體外溶解度
批次：

DMSO : 80 mg/mL ( (200.78 mM) ；DMSO吸濕會(huì)降低化合物溶解度，請(qǐng)使用新開封DMSO)

Water : 80 mg/mL (200.78 mM)

Ethanol : Insoluble

DMSO : 80 mg/mL ( (200.78 mM) ；DMSO吸濕會(huì)降低化合物溶解度，請(qǐng)使用新開封DMSO)

Water : 80 mg/mL (200.78 mM)

Ethanol : Insoluble

摩爾濃度計(jì)算器

體內(nèi)溶解度
批次：

現(xiàn)配現(xiàn)用，請(qǐng)按從左到右的順序依次添加，澄清后再加入下一溶劑

動(dòng)物體內(nèi)配方計(jì)算器

實(shí)驗(yàn)計(jì)算

摩爾濃度計(jì)算器

質(zhì)量	濃度	體積	分子量
=	×	×

稀釋計(jì)算器分子量計(jì)算器

動(dòng)物體內(nèi)配方計(jì)算器（澄清溶液）

第一步：請(qǐng)輸入基本實(shí)驗(yàn)信息（考慮到實(shí)驗(yàn)過程中的損耗，建議多配一只動(dòng)物的藥量）

給藥劑量 mg/kg 動(dòng)物平均體重 g 每只動(dòng)物給藥體積 μL 動(dòng)物數(shù)量只

第二步：請(qǐng)輸入動(dòng)物體內(nèi)配方組成（配方適用于不溶于水的藥物；不同批次藥物配方比例不同，請(qǐng)聯(lián)系Selleck為您提供正確的澄清溶液配方）

% DMSO + % + % Tween 80 + % ddH2O

%DMSO+ %

計(jì)算結(jié)果：

工作液濃度： mg/ml；

DMSO母液配制方法： mg 藥物溶于μL DMSO溶液（母液濃度mg/mL，注：如該濃度超過該批次藥物DMSO溶解度，請(qǐng)先聯(lián)系Selleck）；

體內(nèi)配方配制方法：取μL DMSO母液，加入μL PEG300，混勻澄清后加入μL Tween 80，混勻澄清后加入μL ddH₂O，混勻澄清。

體內(nèi)配方配制方法：取μL DMSO母液，加入μL Corn oil，混勻澄清。

注意：1. 首先保證母液是澄清的；
2.一定要按照順序依次將溶劑加入，進(jìn)行下一步操作之前必須保證上一步操作得到的是澄清的溶液，可采用渦旋、超聲或水浴加熱等物理方法助溶。

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* 必填項(xiàng)

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