GSK-LSD1
Axon 2375
CAS [2102933-95-7]
MF C14H20N2.2HCl
MW 289.24
- Purity: 99%
- Optical purity: mixture of trans-diastereomers
- Soluble in water and DMSO
Description
Irreversible inhibitor of the KDM1 family histone demethylase LSD1 (IC50 value 16 nM). GSK-LSD1 is >1000 fold selective over closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B), induces gene expression changes in cancer cell lines (average EC50 <5 nM), and inhibits cancer cell line growth (average EC50 <5 nM).
Irreversible inhibitor of the KDM1 family histone demethylase LSD1
Chemical name
rel-N-((1R,2S)-2-phenylcyclopropyl)piperidin-4-amine dihydrochloride
Parent CAS No.
[1431368-48-7]
Order
Size | Unit Price | Stock | |
---|---|---|---|
10 mg | €100.00 | In Stock | |
50 mg | €350.00 | In Stock |
Special Offers
Size | Unit Price | Stock | |
---|---|---|---|
2 x 10 mg | €160.00 | In Stock |
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