PLX 4032 - RG 7204 | Vemurafenib | RO 5185426
Axon 1624
CAS [918504-65-1]
MF C23H18ClF2N3O3S
MW 489.92
- Purity: 98%
- Soluble in DMSO
Description
Selective inhibitor of protein kinase, targeting B-Raf (V600E) (IC50: 44 nM); PLX4032 has been shown to cause programmed cell death in melanoma cell lines; a potential anti-tumor agent under clinical trials
B-Raf protein kinase inhibitor
Chemical name
N-(3-(5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
Parent CAS No.
[918504-65-1]