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CAL 101 - Idelalisib

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2170

CAS [870281-82-6]

MF C22H18FN7O
MW 415.42

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO

CAL 101

Description

Orally active and selective inhibitor of PI3K δ-isoform (IC50 p110δ: 2.5nM), displaying clinical activity in chronic lymphocytic leukemia (CLL). Cal 101 is 40- to 300-fold more selective for PI3K-δ (δ) isoform relative vs other PI3K class I enzymes (p110α, p110β, and p110γ IC50 were 820, 565, and 89nM, respectively). It does not promote apoptosis in normal T cells or natural killer cells, nor does it diminish antibody-dependent cellular cytotoxicity.
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Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €335.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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