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Axon 1881
CAS [675576-97-3]
MF C30H30Cl2N4O4MW 581.49
Nutlin-3b is a 150-fold less potent (+)-enantiomer of Nutlin-3 (Axon 1585) as p53 MDM2 antagonist or inhibitor, in comparison with more potent opposite (-)-enantiomer Nutlin-3a (Axon 1880); useful as a negative control for non-Mdm2 related cellular activities.
KEYWORDS: Nutlin-3b | MDM2 inhibitor | Nutlin-3, (+)- | Nutlin3b | Nutlin3 | Nutlin 3b | Nutlin 3 | CAS [675576-97-3] | p53 | HDM-MDM | Inhibitor | Enzymes
4-((4R,5S)-4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one
[675576-97-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
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