98% purity available from supplier Axon Medchem, prime source of life science reagents for your research" />

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AZD1080

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2171

CAS [612487-72-6]

MF C19H18N4O2
MW 334.37

  • Purity: 98%
  • Soluble in DMSO

AZD1080

Description

Potent and selective inhibitor of Glycogen synthase kinase 3 (GSK-3), with Ki values of 6.9 nM and 31 nM for GSK-3α and GSK-3β respectively. In phase 1 clinical studies, AZD1080 inhibits tau phosphorylation in cells expressing human tau and in intact rat brain. Interestingly, subchronic but not acute administration with AZD1080 reverses MK-801-induced deficits, measured by long-term potentiation in hippocampal slices and in a cognitive test in mice.
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5 mg €90.00 In Stock
25 mg €320.00 In Stock
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2 x 5 mg €140.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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