Pifithrin-β - PFT-β | Z-2-035II

Based on 18 reference(s) in Google Scholar 8 10 18

Axon 3051

CAS [60477-34-1]

MF C16H16N2S
MW 268.38

Purity: 99%
Soluble in DMSO

Pifithrin-β

Description

Pifithrin-β is the condensation product of the p53 protein inhibitor Pifithrin-α (Axon 1871). Pifithrin-α is unstable in vitro and is rapidly converted to Pifithrin-β.

N Pietrancosta et al. Novel cyclized Pifithrin-alpha p53 inactivators: synthesis and biological studies. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1561-4.

N Pietrancosta et al. Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism. J Med Chem. 2006 Jun 15;49(12):3645-52.

MI Walton et al. An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines. Mol Cancer Ther. 2005 Sep;4(9):1369-77.

Apoptosis Cell Cycle Regulation Stem Cell p53 Transcription Factors DNA-damage Response Ubiquitin TF class 4.3.1

Inhibitor of p53 protein; Condensation product of Pifithrin-α

Chemical name

2-(4-Methylphenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole

Parent CAS No.

[60477-34-1]

Order

Size	Unit Price	Stock
10 mg	€95.00	In Stock
50 mg	€350.00	In Stock

Special Offers

Size	Unit Price	Stock
2 x 10 mg	€150.00	In Stock
2 x 50 mg	€560.00	In Stock

Need more? Bulk Inquiry

Related Products

Axon ID	Name	Description	From price
1402	NSC 348884	NPM inhibitor		€120.00
1871	Pifithrin-α hydrobromide	Inhibitor of p53 protein		€95.00
2016	NSC 319726	Reactivator of the p53 mutant p53R175		€95.00
2244	SCH 529074	Small molecule activator of mutant p53.		€120.00
2249	Tenovin 6	Small water soluble p53 activator and SIRT inhibitor		€105.00
2319	L 002	Inhibitor of p300 HAT (KAT3B) and p53 acetylation		€80.00
2564	NSC 59984	Activator of p53 that restores WT p53 signaling via p73 activation		€95.00
2841	COTI-2	Reactivator of mutant p53		€125.00
2879	CP 31398	Stabilizer of p53 and inducer of apoptosis		€100.00
3152	PAWI-2	Inhibitor which targets both Wnt signaling and ATM/p53		€120.00
3277	NSC194598	p53 DNA-binding inhibitor		€130.00
4278	Pifithrin-μ	Inhibitor of p53 protein; HSP70 inhibitor	Recently added	€95.00

天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Customer Support

Customer Services

About Axon Medchem

Contact Us

Pifithrin-β - PFT-β | Z-2-035II

Description

Chemical name

Parent CAS No.

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Customer Support

Customer Services

About Axon Medchem

Contact Us

Pifithrin-β - PFT-β | Z-2-035II

Description

Chemical name

Parent CAS No.

Related Products

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Send us a message

Contact Us