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Axon 1487
CAS [209986-17-4]
MF C27H24F2N4O3MW 490.50
Very potent and cell-permeable inhibitor of γ-secretase (GSI); potently inhibits Notch processing (IC50 values to be 2.2 nM in SupT1 cells); inhibits β-ammyloid production in cell culture with an IC50 of 0.3 nM.
KEYWORDS: γ-Secretase Inhibitor BZ | supplier | γ-Secretase inhibitor | Compound E | CAS [209986-17-4] | Amyloids | γ Secretase | γ-Secretase inhibitor (GSI) | Inhibitor | Enzymes
(S)-2-[2-(3,5-Difluoro-phenyl)-acetylamino]-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide
[209986-17-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
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