VX 745

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1811

CAS [209410-46-8]

MF C19H9Cl2F2N3OS
MW 436.26

Purity: 99%
Soluble in DMSO

VX 745

Description

Highly potent and selective inhibitor of p38α MAP kinase (IC50: 10 nM); being 1000 fold selective over closely related kinases

JP Duffy et al. The discovery of VX-745: a novel and selective p38α kinase inhibitor. ACS Med. Chem. Lett. 2011, 2, 758.

MC Bagley et al. Rapid synthesis of VX-745: p38 MAP kinase inhibition in Werner syndrome cells. Bioorg. Med. Chem. Lett. 2007, 17(8), 5107-5110.

JJ Haddad. VX-745. Vertex Pharmaceuticals. Curr. Opin. Investig. Drugs. 2001, 2(8), 1070-1076.

Cell Signaling & Oncology MAPK (p38) MAPK EC 2.7.11.24

Inhibitor of p38α MAP kinase

Chemical name

5-(2,6-dichlorophenyl)-2-(2,4-difluorophenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one

Parent CAS No.

[209410-46-8]

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Size	Unit Price	Stock
5 mg	€90.00	In Stock
25 mg	€330.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	€140.00	In Stock
2 x 25 mg	€480.00	In Stock

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天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

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VX 745

Description

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