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Axon 2817
CAS [1628838-42-5]
MF C28H29F3N4O4MW 542.55
RAF709 is a potent, selective, and efficacious B/C RAF inhibitor with IC50 values of 0.4 nM and 0.5 nM for BRAF and CRAF, respectively. RAF709 was cellularly potent in a KRAS mutant cell line (Calu-6) and was well-tolerated and efficacious in KRAS mutant xenograft models.
KEYWORDS: RAF709 | supplier | B/C RAF inhibitor | RAF 709 | RAF-709 | CAS [1628838-42-5] | MEK | RAF | Inhibitor | Enzymes
N-(2-Methyl-5'-morpholino-6'-(tetrahydro-2H-pyran-4-yloxy)-3,3'-bipyridin-5-yl)-3-(trifluoromethyl)benzamide
[1628838-42-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
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