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Axon 3094
CAS [1628260-79-6]
MF C30H33FN8O2SMW 588.70
GLPG1690 is a first-in-class, potent autotaxin (ATX) inhibitor with a Ki value of 15 nM. GLPG1690 demonstrated signi?cant activity in the mouse BLM-induced ?brosis model at doses of 10 and 30 mg/kg twice a day, with an efficacy comparable or superior to that of the reference compound pirfenidone.
KEYWORDS: GLPG1690 | supplier | ATX inhibitor | Ziritaxestat | GLPG 1690 | GLPG-1690 | CAS [1628260-79-6] | LPC | PDE | Inhibitor | Enzymes | Idiopathic pulmonary fibrosis
2-((2-Ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile
[1628260-79-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
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