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Axon 2795
CAS [1204144-28-4]
MF C21H21N3O2SMW 379.48
AZD1208 is a pan-Pim kinase inhibitor (IC50 values of 0.4 nM, 5.0 nM and 1.9 nM for Pim-1, Pim-2 and Pim-3, respectively) which does not inhibit FLT3. AZD1208 treatment resulted in growth inhibition and cell size reduction in AML cell lines including FLT3-WT (OCI-AML-3, KG-1a, MOLM-16) and FLT3-ITD mutated (MOLM-13, MV-4-11).
KEYWORDS: AZD1208 | supplier | PIM inhibitor | AZD-1208 | AZD 1208 | CAS [1204144-28-4] | Non Selective (Phosphorylation Substrates) | PIM | Inhibitor | Enzymes | AML
(R,Z)-5-((2-(3-Aminopiperidin-1-yl)biphenyl-3-yl)methylene)thiazolidine-2,4-dione
[1204144-28-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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