99% purity available from supplier Axon Medchem, prime source of life science reagents for your research" />

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Brigatinib - AP 26113 | Alunbrig

Based on 123 reference(s) in Google Scholar 8 10 123

Axon 2978

CAS [1197953-54-0]

MF C29H39ClN7O2P
MW 584.09

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

Brigatinib

Description

Brigatinib is a potent and selective inhibitor of ALK (IC50 value of 0.6 nM), capable of overcoming mechanisms of resistance associated with crizotinib (Axon 1660). Besides inhibition of ALK, FLT3 and ROS1 were also potently inhibited. Brigatinib was highly active against both sensitive and resistant H3122 cells, decreasing cell growth, suppressing ALK phosphorylation, and inducing apoptosis.

KEYWORDS: Brigatinib | supplier | ALK inhibitor | AP 26113 | Alunbrig | AP26113 | AP-26113 | CAS [1197953-54-0] | Non Selective | ALK | ROS | FLT3 | Inhibitor | Receptors | EML4-ALK | Anaplastic Lymphoma Kinase

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Size Unit Price Stock
10 mg €80.00 In Stock
50 mg €240.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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