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6-Bromo-1,3-benzoxazole

CAS: 375369-14-5 | OR43655 | 6-Bromo-1,3-benzoxazole

Catalogue Number OR43655

Synonym(s): 6-Bromobenzo[d]oxazole

6-Bromo-1,3-benzoxazole (CAS: 375369-14-5) is an organic building block used in the preparation of agrochemical and pharmaceutical components. It can be used as an electrophilic partner i... Read More

CAS Number

375369-14-5

Commodity Code

2934999090

MDL Number

MFCD03092891

Purity
98%
Formula Weight
198.02 g/mol
Chemical Hazard
Harmful/Irritant
GHS
Hazard Statements
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H302+312+332: Harmful if swallowed, in contact with skin or if inhaled.
Precautionary Statements
P261: Avoid breathing <dust/fumes/gas/mist/vapours/spray>. P271: Use only outdoors or in a well-ventilated area. P280: Wear <protective gloves/protective clothing/eye protection/face protection>.: hazard.P261: Avoid breathing <dust/fumes/gas/mist/vapours/spray>. P271: Use only outdoors or in a well-ventilated area. P280: Wear <protective gloves/protective clothing/eye protection/face protection>.
MSDS
View MSDS
Typical Batch COA
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Size
UK Stock
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US Stock
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Price
Quantity
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5g
Out of Stock
Out of Stock
£103.00
25g
Out of Stock
Out of Stock
£503.00
Size 5g
Price £103.00
UK Stock Out of Stock
US Stock Out of Stock
Size 25g
Price £503.00
UK Stock Out of Stock
US Stock Out of Stock

Product Description

6-Bromo-1,3-benzoxazole (CAS: 375369-14-5) is an organic building block used in the preparation of agrochemical and pharmaceutical components. It can be used as an electrophilic partner in a variety of palladium-catalysed cross coupling reactions. It has also been used in the synthesis of TS33 inhibitors as antibiotics,[1] and in the synthesis of a class of tetrahydroisoquinoline derivatives as pan-KRAS inhibitors for the treatment of cancer.[2]

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1) https://www.sciencedirect.com/science/article/abs/pii/S0022286022024723?via%3Dihub

2) https://worldwide.espacenet.com/patent/search/family/082670118/publication/CN114874201A?q=pn%3DCN114874201B