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Tamibarotene

Catalog No.
A3856
RARα agonist
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$61.00
In stock
10mg
$55.00
In stock
50mg
$99.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Tamibarotene, Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Tamibarotene exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt351.44
Cas No.94497-51-5
FormulaC22H25NO3
SynonymsAm80;Am 80;Am-80
Solubilityinsoluble in H2O; ≥13.35 mg/mL in DMSO; ≥52.5 mg/mL in EtOH with ultrasonic
Chemical Name4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid
SDFDownload SDF
Canonical SMILESCC1(CCC(C2=C1C=CC(=C2)NC(=O)C3=CC=C(C=C3)C(=O)O)(C)C)C
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Chemical structure

Tamibarotene