Ethambutol

Catalog No.

B3418

bacteriostatic antimycobacterial agent

Grouped product items
Size	Price	Stock	Qty
1g	$80.00	Please inquire
5g	$320.00	Please inquire

For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Background

Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

Storage	Store at -20°C
M.Wt	204.31
Cas No.	74-55-5
Formula	C₁₀H₂₄N₂O₂
Solubility	Soluble in DMSO
Chemical Name	(2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol
SDF	Download SDF
Canonical SMILES	CCC(CO)NCCNC(CC)CO
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Cell experiment [1]:
Cell lines	M.smegmatis, M.avium
Preparation method	The solubility of this compound in DMSO is soluble. General tips for obtaining a higher concentration: Please warm the tube at 37 ℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.
Reacting condition	0.18mg/L, 15mg/L
Applications	The MIC of ethambutol for M.smegmatis and M.avium is 0.18mg/L, 15mg/L respectively.
Animal experiment [1]:
Animal models	Mice infected with Mycobacterium tuberculosis and Mycobacterium avium
Dosage form	100 mg/kg, gavage, once a week for 5 weeks
Application	Ethambutol is effective in animal models. Compared to untreated, ethambutol-treated mice resulted in lower log CFU.
Other notes	Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal.
References: [1]. Kaur D, Khuller GK. In vitro, ex-vivo and in vivo activities of ethambutol and sparfloxacin alone and in combination against mycobacteria. Int J Antimicrob Agents. 2001 Jan;17(1):51-5. PubMed PMID: 11137649.

Purity = 98.00%