Berbamine hydrochloride

Catalog No.

N2471

Anticancer drug,novel inhibitor of NF-κB activity

Grouped product items
Size	Price	Stock	Qty
1g	$100.00	In stock

For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Background

Extracted?from?berberidis;Store?the?product?in?sealed,?cool?and?dry?condition

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	681.65
Cas No.	6078-17-7
Formula	C₃₇H₄₂Cl₂N₂O₆
Solubility	≥68 mg/mL in DMSO; ≥10.68 mg/mL in H2O; ≥4.57 mg/mL in EtOH
Chemical Name	(11S,31R)-16,36,37-trimethoxy-12,32-dimethyl-11,12,13,14,31,32,33,34-octahydro-2,6-dioxa-1(7,1),3(8,1)-diisoquinolina-5(1,3),7(1,4)-dibenzenacyclooctaphan-54-ol dihydrochloride
SDF	Download SDF
Canonical SMILES	COC1=CC2=C(C(OC3=CC([C@@](CC4=CC=C5C=C4)([H])N(C)CC6)=C6C=C3OC)=C1OC)[C@](CC7=CC=C(O)C(O5)=C7)([H])N(C)CC2.Cl.Cl
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Biological Activity

Description	Berbamine hydrochloride is the next generation anticancer drug with IC50 values of 5.83 μg/ml (24h) and 34.5 μM for KU812 and HepG2 cells, respectively.
Targets	KU812	HepG2	MCF-7/ADR	KBv200	K562
IC50	5.83 μg/ml (24h)	34.5 μM

Purity = 97.40%