Withaferin A
Catalog No.
B7199
Prevents NF-κB activation by inhibiting activation of IKKβ
Featured Products
- 1. Jiyoung Jang, Hyun Jung Park, et al. "Vimentin-mediated buffering of internal integrin β1 pool increases survival of cells from anoikis." BMC Biol. 2024 Jun 24;22(1):139. PMID: 38915055
- 2. Kim J, Jang J, et al. "Vimentin filament controls integrin α5β1-mediated cell adhesion by binding to integrin through its Ser38 residue." FEBS Lett. 2016 Oct;590(20):3517-3525. PMID:27658040
| Physical Appearance | A crystalline solid |
| Storage | Desiccate at -20°C |
| M.Wt | 470.6 |
| Cas No. | 5119-48-2 |
| Formula | C28H38O6 |
| Solubility | Soluble in DMSO |
| Chemical Name | (4S,4aR,5aR,6aS,6bS,9R,9aS,11aS,11bR)-4-hydroxy-9-((S)-1-((R)-5-(hydroxymethyl)-4-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl)-9a,11b-dimethyl-5a,6,6a,6b,7,8,9,9a,10,11,11a,11b-dodecahydrocyclopenta[1,2]phenanthro[8a,9-b]oxiren-1(4H)-one |
| SDF | Download SDF |
| Canonical SMILES | O[C@@H](C=C1)[C@@]23O[C@@H]2C[C@@H]([C@H]4[C@@]5(C)[C@@H]([C@H](C)[C@@H](CC(C)=C6CO)OC6=O)CC4)[C@H](CC5)[C@]3(C1=O)C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity ≥95.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
Related Biological Data
