ZM 449829
Catalog No.
A4517
JAK3 inhibitor
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Potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3) which binds competitively to the JAK3 ATP site. pIC50 values are 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively.
| Physical Appearance | A solid |
| Storage | Desiccate at -20°C |
| M.Wt | 182.22 |
| Cas No. | 4452-06-6 |
| Formula | C13H10O |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥8.2 mg/mL in DMSO |
| Chemical Name | 1-(naphthalen-2-yl)prop-2-en-1-one |
| SDF | Download SDF |
| Canonical SMILES | O=C(C=C)C1=CC2=C(C=C1)C=CC=C2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
