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Metoclopramide

Catalog No.
A3599
Dopamine receptor antagonist
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$72.00
In stock
100mg
$66.00
In stock
500mg
$132.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Metoclopramide is a dopamine receptor antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is the antiemetic drug of choice in pregnant women. Findings provide reassurance regarding the safety of metoclopramide for the fetus when the drug is given to women to relieve nausea and vomiting during pregnancy. Evidence also supports its use for gastroparesis (poor stomach emptying) and gastroesophageal reflux disease. It appears to bind to dopamine D2 receptors where it is a receptor antagonist, and is also a mixed 5-HT3 receptor antagonist/ 5-HT4 receptor agonist.

Chemical Properties

StorageStore at -20°C
M.Wt299.8
Cas No.364-62-5
FormulaC14H22ClN3O2
Solubilityinsoluble in H2O; ≥14.99 mg/mL in DMSO; ≥24.6 mg/mL in EtOH with gentle warming
Chemical Name4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
SDFDownload SDF
Canonical SMILESCCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control