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Ciliobrevin A

Catalog No.
A8655
Hh pathway antagonist
Grouped product items
SizePriceStock Qty
5mg
$76.00
Ship with 10-15 days
10mg
$100.00
Ship with 10-15 days
25mg
$222.00
Ship with 10-15 days
50mg
$405.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Hedgehog (Hh) pathway antagonist; blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo. Peturbs primary cilia formation; inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity.

Chemical Properties

Physical AppearanceYellow solid
StorageStore at -20°C
M.Wt358.18
Cas No.302803-72-1
FormulaC17H9Cl2N3O2
SolubilitySoluble in DMSO
Chemical Name(2E)-3-(2,4-dichlorophenyl)-3-oxo-2-(4-oxo-1H-quinazolin-2-ylidene)propanenitrile
SDFDownload SDF
Canonical SMILESC1=CC=C2C(=C1)C(=O)NC(=C(C#N)C(=O)C3=C(C=C(C=C3)Cl)Cl)N2
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Ciliobrevin A