Fumagillin
Catalog No.
A4407
Antibiotic and antiangiogenic agent
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Antibiotic and antiangiogenic agent; covalently binds and inhibits methionine aminopeptidase-2. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo. Also inhibits tumor growth in mice. Analog available, TNP 470 (Cat.No. 3750).
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 458.55 |
| Cas No. | 23110-15-8 |
| Formula | C26H34O7 |
| Solubility | insoluble in H2O; ≥2.58 mg/mL in EtOH with ultrasonic; ≥81.3 mg/mL in DMSO |
| Chemical Name | 10-[[5-methoxy-4-[2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid |
| SDF | Download SDF |
| Canonical SMILES | CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
