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Tiotropium Bromide

Catalog No.
A3874
MAChR M antagonist
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$50.00
In stock
100mg
$133.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR M) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. This stops signaling between neurons and leads to muscle relaxation. Tiotropium Bromide is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. Tiotropium Bromide improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt472.42
Cas No.136310-93-5
FormulaC19H22BrNO4S2
SynonymsTiopropium
Solubility≥23.62 mg/mL in DMSO; insoluble in EtOH; ≥33.07 mg/mL in H2O with ultrasonic
Chemical Name(1R,2R,4S,5S,7s)-7-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide
SDFDownload SDF
Canonical SMILESO=C(C(C1=C([H])C([H])=C([H])S1)(C2=C([H])C([H])=C([H])S2)O[H])O[C@@]3([H])C([H])([H])[C@]4([H])[N+](C([H])([H])[H])(C([H])([H])[H])[C@@](C3([H])[H])([H])[C@@]5([H])O[C@@]45[H].[Br-]
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Chemical structure

Tiotropium Bromide