Safinamide
Catalog No.
A3784
MAO-B inhibitor
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Safinamide (EMD 1195686; FCE 26743; ) is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, Safinamide (EMD 1195686; FCE 26743; ) is voltage-dependent sodium and calcium channel blocker. Safinamide (EMD 1195686; FCE 26743; ) appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals.
| Storage | Store at -20°C |
| M.Wt | 302.34 |
| Cas No. | 133865-89-1 |
| Formula | C17H19FN2O2 |
| Synonyms | EMD 1195686;FCE 26743;EMD-1195686;EMD1195686;FCE-26743 |
| Solubility | ≥32.3 mg/mL in DMSO; ≥13.95 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide |
| SDF | Download SDF |
| Canonical SMILES | CC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
