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[ CAS No. 93107-30-3 ] {[proInfo.proName]}

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Chemical Structure| 93107-30-3
Chemical Structure| 93107-30-3
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Quality Control of [ 93107-30-3 ]

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Product Details of [ 93107-30-3 ]

CAS No. :93107-30-3 MDL No. :MFCD01646375
Formula : C13H9F2NO3 Boiling Point : No data available
Linear Structure Formula :- InChI Key :KNEXGVPHPGXAGF-UHFFFAOYSA-N
M.W : 265.21 Pubchem ID :5210422
Synonyms :

Safety of [ 93107-30-3 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P280-P305+P351+P338 UN#:
Hazard Statements:H302-H315-H319-H332-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 93107-30-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 93107-30-3 ]

[ 93107-30-3 ] Synthesis Path-Downstream   1~12

  • 1
  • [ 503-29-7 ]
  • [ 93107-30-3 ]
  • 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[1'-azetidinyl]-4-oxo-3-quinoline-carboxylic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; EXAMPLE 1 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[1'-azetidinyl]-4-oxo-3-quinoline-carboxylic acid A mixture of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid (1.591 g, 6 mmole), acetonitrile (70 ml), azetidine (390 mg, 6.8 mmole) and DBU (913 mg, 6 mmole) were heated at reflux. After only 5 minutes of heating, it was observed that crystalline material was precipitating. After 5 additional minutes of heating, the hot solution was filtered. The reaction mixture was then allowed to cool at room temperature for 1 hour. The solid material that precipitated was collected by filtration, washed first with acetonitrile and then with ethyl ether and then dried to give 650 mg of the title compound, m.p. 298°-299° C. (dec.). NMR(DMSO-D6): 1.12-1.13 d and 1.26-1.28 d, 4H of cyclopropane; 2.3-2.4, m, 2H of C3 'azetidine; 3.2-3.7, q, 1H of cyclopropane; 4.19-4.24, q, 4H of azetidine C2 ' and C4 '; 6.82- 6.85, d, 1H of C8; 7.74-7.78, d, 1H of C5; 8.55, s, 1H of C2.
  • 2
  • [ 110-85-0 ]
  • [ 93107-30-3 ]
  • [ 93107-08-5 ]
  • 3
  • [ 505-66-8 ]
  • [ 93107-30-3 ]
  • [ 118330-11-3 ]
  • 4
  • [ 90152-00-4 ]
  • [ 93107-30-3 ]
  • [ 118382-88-0 ]
  • 5
  • [ 5625-67-2 ]
  • [ 93107-30-3 ]
  • [ 103237-52-1 ]
  • 6
  • [ 45347-82-8 ]
  • [ 93107-30-3 ]
  • 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[3'-hydroxy-1'-azetidinyl]-4-oxo-3-quinolinecarboxylic acid [ No CAS ]
  • 7
  • [ 127371-54-4 ]
  • [ 93107-30-3 ]
  • 8
  • methyl 2-cyclopropylaminomethylene-3-(2,4,5-trifluorophenyl)-3-oxopropanoate [ No CAS ]
  • [ 93107-30-3 ]
  • 9
  • [ 93107-30-3 ]
  • 1-Cyclopropyl-6-fluoro-7-((S)-3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]
  • 10
  • [ 93107-30-3 ]
  • 1-Cyclopropyl-6-fluoro-7-((R)-3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; hydrochloride [ No CAS ]
  • 11
  • [ 93107-30-3 ]
  • 7-((3S)-amino-(4R)-ethylpiperidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid dihydrochloride [ No CAS ]
  • 12
  • [ 93107-30-3 ]
  • 1-Cyclopropyl-6-fluoro-7-((2R,3S)-2-methyl-3-methylamino-azetidin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid [ No CAS ]
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