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CAS No. : | 78-26-2 | MDL No. : | MFCD00004696 |
Formula : | C7H16O2 | Boiling Point : | - |
Linear Structure Formula : | HOCH2C(CH3)(C3H7)CH2OH | InChI Key : | JVZZUPJFERSVRN-UHFFFAOYSA-N |
M.W : | 132.20 | Pubchem ID : | 66220 |
Synonyms : |
|
Chemical Name : | 2-Methyl-2-propylpropane-1,3-diol |
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P280-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H302-H315-H319-H332-H335 | Packing Group: | N/A |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
80% | With toluene-4-sulfonic acid; In toluene; at 110℃; for 24h; | As shown in Scheme 5 below, to 100 mL of toluene in which 5.28 g (27.7 mmol) of p-toluenesulfonic acid (p-TSA ), 20.0 g (138.7 mmol) of <strong>[51792-34-8]3,4-dimethoxythiophene</strong> (compound (1)) and 2-methyl-2-Propyl-1,3-propanediol, compound (8)) were mixed and stirred at 110 DEG C for 24 hours. After completion of the reaction, a mixed solvent of water and ethyl acetate (EtOAc) was added to the reaction product, extracted, washed with brine, water removed using anhydrous Na2SO4, filtered and concentrated. The water was separated by column chromatography on SiO2 (eluent: hexane: ethyl acetate = 10: 1) to give 3-methyl-3-propyl-3,4-dihydro-2H-thieno [3,4-b] [1,4] dioxepin -B] [1,4] dioxepine, compound (9)) (yield: 65-80percent). Of the obtained compound 1H-NMR the data is as follows : 1H-NMR (CDCl3, Varian 400 MHz) : delta 0.93-0.96 (6H, m), 1.29-1.45 (4H, m), 3.69-3.88 (4H,m), 6.45 (2H, s). |
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