[ CAS No. 608-30-0 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}

Cat. No.: {[proInfo.prAm]}

2D 3D

Structure of 608-30-0 * Storage: {[proInfo.prStorage]}

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	Inquiry	{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price) ]}	{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price) ]}	{[ item.pr_usastock ]}		{[ item.pr_chinastock ]}	{[ item.pr_remark ]}	Login		Inquiry

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

For Research Only 120K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 608-30-0 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 608-30-0 ]

SDS Specification

Alternatived Products of [ 608-30-0 ]

Product Details of [ 608-30-0 ]

CAS No. :	608-30-0	MDL No. :	MFCD00007638
Formula :	C₆H₅Br₂N	Boiling Point :	No data available
Linear Structure Formula :	-	InChI Key :	XIRRDAWDNHRRLB-UHFFFAOYSA-N
M.W :	250.92	Pubchem ID :	69098
Synonyms :

Calculated chemistry of [ 608-30-0 ] Expand+

Physicochemical Properties

Num. heavy atoms :	9
Num. arom. heavy atoms :	6
Fraction Csp3 :	0.0
Num. rotatable bonds :	0
Num. H-bond acceptors :	0.0
Num. H-bond donors :	1.0
Molar Refractivity :	46.25
TPSA :	26.02 ?2

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	Yes
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	Yes
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-5.97 cm/s

Lipophilicity

Log Po/w (iLOGP) :	2.1
Log Po/w (XLOGP3) :	2.62
Log Po/w (WLOGP) :	2.8
Log Po/w (MLOGP) :	2.99
Log Po/w (SILICOS-IT) :	2.5
Consensus Log Po/w :	2.6

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	1.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-3.54
Solubility :	0.0724 mg/ml ; 0.000289 mol/l
Class :	Soluble
Log S (Ali) :	-2.82
Solubility :	0.383 mg/ml ; 0.00153 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-3.75
Solubility :	0.0448 mg/ml ; 0.000179 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	1.0 alert
Leadlikeness :	0.0
Synthetic accessibility :	1.32

Safety of [ 608-30-0 ]

Signal Word:	Warning	Class:
Precautionary Statements:	P261-P280-P305+P351+P338	UN#:
Hazard Statements:	H315-H317-H319-H335	Packing Group:
GHS Pictogram:

Application In Synthesis of [ 608-30-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 608-30-0 ]
Downstream synthetic route of [ 608-30-0 ]

[ 608-30-0 ] Synthesis Path-Upstream 1~1

1
[ 608-30-0 ]
[ 1435-54-7 ]

Yield	Reaction Conditions	Operation in experiment
29%	Stage #1: at 0 - 10℃; for 1 h; Stage #2: at 0 - 220℃; for 3 h;	Step 1: 1,3-dibromo-2-fluorobenzene To a mixture of 2,6-dibromoaniline (5.0 g, 20 mmol) and HCl (12 N, 10 mL) was added NaNO₂ (2.1 g, 30 mmol) at 0° C. The reaction mixture was stirred at 0-10° C. for 1 h, and then NH₄BF₄ solution (4.2 g, 40 mmol) was added dropwise. The reaction mixture was stirred at 0-10° C. for 1 h. The precipitate was filtered and dried. The residue obtained was heated to 220° C. for 2 h, cooled to rt and dissolved with EA (150 mL), washed with NaOH (2 N, 200 mL). The organic layer was dried over Na₂SO₄, filtered and concentrated under reduced pressure to give 1,3-dibromo-2-fluorobenzene (1.45 g, yield 29percent).

Reference： [1] Patent: US2013/131016, 2013, A1, . Location in patent: Paragraph 0352; 0353
[2] Acta Chimica Academiae Scientiarum Hungaricae, 1957, vol. 10, p. 227,229

[ 608-30-0 ] Synthesis Path-Downstream 1~11

1
[ 608-30-0 ]
[ 608-21-9 ]

Yield	Reaction Conditions	Operation in experiment
80%	With tert.-butylnitrite; copper(ll) bromide; In acetonitrile; at 60℃; for 1h;	In a 500-mL round-bottom flask was dissolved 5.78 g (25.9 mmol) of CuBr2 in 200 mL of dry CH3CN and the mixture heated to 60 C. To this warm solution was added 3.80 mL (31.9 mmol) tert-butyl nitrite, followed by a solution of 5.01 g (19.9 mmol) of commercially available 2,6-dibromoaniline 22 in 50 mL CH3CN. The mixture was stirred at 60 C for 1 h, then cooled to room temperature and poured into 200 mL 20% aqueous ammonia. The mixture was extracted with hexane (2 x 200 mL) and the combined organic phase was washed sequentially with 20% aqueous ammonia (100 mL), water (100 mL), brine (50 mL), and then dried over anhydrous magnesium sulfate. The contents were filtered and concentrated under reduced pressure. The resulting crude material was recrystallized from ethanol to give 5.12 g (80%) of 1,2,3-tribromobenzene 23 as an off-white solid, mp = 88-90 C. 1H NMR (CDCl3): d 7.58 (d, J = 8.0 Hz, 2 H), 7.03 (t, J = 8.0 Hz, 1H); 13C NMR (CDCl3): d 132.6, 129.2, 127.7, 126.2. The physical and spectral data is consistent with that which was previously reported for this compound: (1) Menzel, K.; Fisher, E. L.; DiMichele, L.; Frantz, D. E.; Nelson, T. D.; Kress, M. H. J. Org. Chem. 2006, 71, 2188-2191; (2) Teclechiel, D.; Sundstroem, M.; Marsh, G. Chemosphere 2009, 74, 421-427. The second reference includes low resolution mass spectral data.

Reference： [1]Tetrahedron Letters,2013,vol. 54,p. 913 - 917
[2]Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti,1908,vol. <5> 17 I,p. 473

2
[ 608-30-0 ]
[ 1435-54-7 ]

Yield	Reaction Conditions	Operation in experiment
29%		Step 1: 1,3-dibromo-2-fluorobenzene To a mixture of 2,6-dibromoaniline (5.0 g, 20 mmol) and HCl (12 N, 10 mL) was added NaNO2 (2.1 g, 30 mmol) at 0° C. The reaction mixture was stirred at 0-10° C. for 1 h, and then NH4BF4 solution (4.2 g, 40 mmol) was added dropwise. The reaction mixture was stirred at 0-10° C. for 1 h. The precipitate was filtered and dried. The residue obtained was heated to 220° C. for 2 h, cooled to rt and dissolved with EA (150 mL), washed with NaOH (2 N, 200 mL). The organic layer was dried over Na2SO4, filtered and concentrated under reduced pressure to give 1,3-dibromo-2-fluorobenzene (1.45 g, yield 29percent).

Reference： [1]Patent: US2013/131016,2013,A1 .Location in patent: Paragraph 0352; 0353
[2]Acta Chimica Academiae Scientiarum Hungaricae,1957,vol. 10,p. 227,229

3
[ 39150-45-3 ]
[ 608-30-0 ]

Yield	Reaction Conditions	Operation in experiment
	With sulfuric acid; In water; at 170℃; for 3.0h;	To a mixture of 50.0 g sulfanilamide, 850 mL water and 200 mL 48% HBr solution, 90.0 g sodium perborate was added at 85 C. The mixture was stirred at 80-85 C for 30 min and then was cooled to room temperature and filtered. The residue was washed to be neutral by water. The solid was desulfonated by reacting with 70% sulfuric acid solution for 3 h under reflux. Crude product was obtained by steam distillation and further purified by recrystallization in ethanol. 1H NMR (500 MHz, CDCl3, delta in ppm): 7.35-7.40 (d, 2H, Ar-Hm), 6.5 (t, 1H, Ar-Hp).

Reference： [1]Organic Syntheses,1944,vol. 24,p. 48
[2]Monatshefte fur Chemie,1915,vol. 36,p. 132
[3]Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical,1989,vol. 28,p. 472 - 476
[4]Journal of Molecular Catalysis A: Chemical,2014,vol. 390,p. 76 - 82

4
[ 7664-93-9 ]
[ 39150-45-3 ]
[ 608-30-0 ]

Reference： [1]Monatshefte fur Chemie,1915,vol. 36,p. 132

5
[ 7664-93-9 ]
[ 39150-45-3 ]
[ 608-30-0 ]
[ 147-82-0 ]

Reference： [1]Archiv der Pharmazie,1943,vol. 281,p. 193,200

6
[ 608-30-0 ]
[ 89694-46-2 ]
[ 1257236-13-7 ]

Yield	Reaction Conditions	Operation in experiment
47%	With sodium carbonate;tetrakis(triphenylphosphine) palladium(0); In 1,4-dioxane; at 150℃; for 1h;Microwave irradiation;	<strong>[89694-46-2]2-chloro-5-methoxyphenylboronic acid</strong> (1.25 g, 6.71 mmol), 2,6-dibromoaniline (1.851 g, 7.38 mmol), sodium carbonate (6.71 mL, 13.41 mmol) and tetrakis(triphenylphosphine)palladium(0) (0.465 g, 0.40 mmol) were dissolved in dioxane (10 mL), degassed and sealed into a microwave tube. The reaction was heated to 1500C for 1 hour in the microwave reactor and cooled to room temperature.The reaction mixture was poured into saturated aqueous NH4CI solution (100 mL), extracted with EtOAc (100 mL), and the organic layer was washed with water (50 mL) and saturated brine (50 mL). The organic layer was dried over MgSO4, filtered and evaporated to afford an orange oil. The crude product was purified by flash silica chromatography, elution gradient 0 to 10percent EtOAc in isohexane. Pure fractions were evaporated to dryness to afford 3-bromo-2'- chloro-5'-methoxybiphenyl-2-amine (0.993 g, 47 percent) as a white solid; 1H NMR (400 MHz, CDCI3) delta 3.73 (3H, s), 3.95 (2H, s), 6.61 (1 H, t), 6.73 - 6.78 (1 H, m), 6.83 (1 H, d), 6.92 - 6.94 (1 H, m), 7.31 - 7.34 (1 H, m), 7.38 - 7.40 (1 H, m)

Reference： [1]Organic and Biomolecular Chemistry,2011,vol. 9,p. 6066 - 6074
[2]Patent: WO2010/136778,2010,A1 .Location in patent: Page/Page column 43

7
[ 608-30-0 ]
[ 331646-99-2 ]

Reference： [1]Organic Letters,2011,vol. 13,p. 676 - 679

8
[ 608-30-0 ]
[ 219735-99-6 ]
[ 1332939-47-5 ]

Reference： [1]Organic and Biomolecular Chemistry,2011,vol. 9,p. 6066 - 6074

9
[ 1122-12-9 ]
[ 608-30-0 ]
3,4-dibromo-1-(2,6-dibromophenyl)-1H-pyrrole-2,5-dione [ No CAS ]

Reference： [1]European Journal of Organic Chemistry,2013,p. 8094 - 8096

10
[ 608-30-0 ]
[ 172732-52-4 ]
[ 946147-06-4 ]

Yield	Reaction Conditions	Operation in experiment
36.7%	With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate monohydrate; In toluene; at 100℃; for 6h;Inert atmosphere;	Step 1: Synthesis of 4-bromo-6-aminophenanthridine A three neck 1 L round bottom flask was charged with 2,6-dibromoaniline (143.51 g, 0.57 mole), 2-cyanophenylbornic acid trimethylene ester (34.35 g, 0.19 mole), K3PO4. H2O (43.89 g, 0.1906 mole), PdCl2(PPh3)2 (6.67 g, 9.5 mmole) and anhydrous toluene (700 ml). The reaction mixture was heated to 100° C. under nitrogen for 6 hrs. The reaction mixture was then concentrated to dryness and subjected to column chromatography to obtain the title compound (19.11 g, 36.7percent).

Reference： [1]Patent: US9281483,2016,B2 .Location in patent: Page/Page column 86; 87

11
[ 870119-58-7 ]
[ 608-30-0 ]
C₄₂H₂₉N₃ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
43%	With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In tetrahydrofuran; water;Reflux;	15.0 g (59.8 mmol) of Intermediate (2,6-dibromoaniline), 53.0 g (143 mmol) of <strong>[870119-58-7]9-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-9H-carbazole</strong>, 6.91 g (5.98 mmol) of tetrakistriphenylphosphine palladium(0) (Pd(PPh3)4), and 41.3 g (299 mmol) of potassium carbonate were added to a solution of 260 ml of THF and 130 ml of water and mixed. The mixed solution was stirred under reflux. After completion of the reaction, the resulting reaction solution was cooled to room temperature, and an extraction process was performed thereon to remove an aqueous solution layer therefrom. The obtained residue was filtered through silica gel under reduced pressure, and the filtrate was concentrated under reduced pressure. The resulting residue was then separated by silica gel column chromatography, thereby providing 14.8 g (yield: 43%) of a desired compound, Intermediate (AA). LC-Mass (cald: 575.24 g/mol, found: M+1=576 g/mol).

Reference： [1]Patent: US2017/369439,2017,A1 .Location in patent: Paragraph 0549-0552

Recommend Products

Same Skeleton Products

Related Products

Isomers

Technical Information

? Alkyl Halide Occurrence ? Benzylic Oxidation ? Birch Reduction ? Blanc Chloromethylation ? Buchwald-Hartwig C-N Bond and C-O Bond Formation Reactions ? Chan-Lam Coupling Reaction ? Friedel-Crafts Reaction ? General Reactivity ? Grignard Reaction ? Hiyama Cross-Coupling Reaction ? Hydride Reductions ? Hydrogenolysis of Benzyl Ether ? Kinetics of Alkyl Halides ? Kumada Cross-Coupling Reaction ? Leuckart-Wallach Reaction ? Mannich Reaction ? Petasis Reaction ? Preparation of Alkylbenzene ? Preparation of Amines ? Reactions of Alkyl Halides with Reducing Metals ? Reactions of Amines ? Reactions of Benzene and Substituted Benzenes ? Reactions of Dihalides ? Specialized Acylation Reagents-Vilsmeier Reagent ? Stille Coupling ? Substitution and Elimination Reactions of Alkyl Halides ? Suzuki Coupling ? Ugi Reaction ? Vilsmeier-Haack Reaction

Historical Records

Related Functional Groups of
[ 608-30-0 ]

Aryls

[ 25462-61-7 ]

2,5-Dibromobenzene-1,4-diamine

Similarity: 0.97

[ 69272-50-0 ]

3,6-Dibromobenzene-1,2-diamine

Similarity: 0.85

[ 1575-36-6 ]

3-Bromobenzene-1,2-diamine

Similarity: 0.85

[ 626-40-4 ]

3,5-Dibromoaniline

Similarity: 0.84

[ 6832-87-7 ]

2-Bromo-N-methylaniline

Similarity: 0.83

Bromides

[ 25462-61-7 ]

2,5-Dibromobenzene-1,4-diamine

Similarity: 0.97

[ 69272-50-0 ]

3,6-Dibromobenzene-1,2-diamine

Similarity: 0.85

[ 1575-36-6 ]

3-Bromobenzene-1,2-diamine

Similarity: 0.85

[ 626-40-4 ]

3,5-Dibromoaniline

Similarity: 0.84

[ 6832-87-7 ]

2-Bromo-N-methylaniline

Similarity: 0.83

Amines

[ 25462-61-7 ]

2,5-Dibromobenzene-1,4-diamine

Similarity: 0.97

[ 69272-50-0 ]

3,6-Dibromobenzene-1,2-diamine

Similarity: 0.85

[ 1575-36-6 ]

3-Bromobenzene-1,2-diamine

Similarity: 0.85

[ 626-40-4 ]

3,5-Dibromoaniline

Similarity: 0.84

[ 6832-87-7 ]

2-Bromo-N-methylaniline

Similarity: 0.83

Ghs Precautionary Statements

Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

[ CAS No. 608-30-0 ] {[proInfo.proName]}

Quality Control of [ 608-30-0 ]

Related Doc. of [ 608-30-0 ]

Product Details of [ 608-30-0 ]

Calculated chemistry of [ 608-30-0 ] Expand+

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 608-30-0 ]

Application In Synthesis of [ 608-30-0 ]

[ 608-30-0 ] Synthesis Path-Upstream 1~1

[ 608-30-0 ] Synthesis Path-Downstream 1~11

Technical Information

Related Functional Groups of [ 608-30-0 ]

Aryls

Bromides

Amines

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 608-30-0 ]