天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Home Cart 0 Sign in  

[ CAS No. 486422-05-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 486422-05-3
Chemical Structure| 486422-05-3
Structure of 486422-05-3 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 486422-05-3 ]

Related Doc. of [ 486422-05-3 ]

Alternatived Products of [ 486422-05-3 ]
Product Citations

Product Details of [ 486422-05-3 ]

CAS No. :486422-05-3 MDL No. :MFCD07368237
Formula : C14H22BNO4S Boiling Point : -
Linear Structure Formula :- InChI Key :YFEWVSRTWWHXFP-UHFFFAOYSA-N
M.W : 311.20 Pubchem ID :16414207
Synonyms :

Safety of [ 486422-05-3 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 486422-05-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 486422-05-3 ]

[ 486422-05-3 ] Synthesis Path-Downstream   1~12

  • 1
  • [ 486422-05-3 ]
  • [ 1152473-40-9 ]
  • [ 1152473-60-3 ]
YieldReaction ConditionsOperation in experiment
57% With water; sodium hydrogencarbonate;tetrakis(triphenylphosphine) palladium(0); In N,N-dimethyl-formamide; at 100.0℃; for 15.0h; To a solution of Compound 1 (lOOmg, 0.228mmol) and 3-(4,4,5,5-tetramethyl- l,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzenesulfonamide (106mg, 0.34mmol) in DMF (3mL) were added 2M aq. NaHCO3 (350μL) and Pd[PPh3J4 (26mg, 0.02mmol). The reaction was heated at 10O 0C for 15 h, allowed to cool, and then diluted with water (2OmL). The resultant precipitate was collected by filtration and air-dried. The crude product was re-dissolved in hot methanol/DMF, filtered hot, and then sufficient water was added to cause the solution to become cloudy. After cooling to room temperature and then further in an ice-bath, the solid was collected by filtration, washed with water and air-dried, followed by further drying under reduced pressure. This provided Compound 12 as a yellow/brown solid (65mg, 57%).
  • 2
  • [ 486422-05-3 ]
  • (S)-8-iodo-N-(1-methoxypropan-2-yl)-5-((tetrahydro-2H-pyran-4-yl)oxy)pyrido[4,3-d]pyrimidin-2-amine [ No CAS ]
  • (S)-3-(2-((1-methoxypropan-2-yl)amino)-5-((tetrahydro-2H-pyran-4-yl)oxy)pyrido[4,3-d]pyrimidin-8-yl)-N,N-dimethylbenzenesulfonamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
30% With potassium phosphate; palladium diacetate; catacxium A; In butan-1-ol; at 50.0℃; for 16.0h;Inert atmosphere; A solution of 8-iodo-N-[(l S)-2-methoxy-l-methyl-ethyl]-5-tetrahydropyran-4-yloxy- pyrido [4,3-d]pyrimidin-2-amine (100 mg, 225 umol, 1 eq), N,N-dimethyl-3-(4,4,5,5- tetramethyl-l,3,2-dioxaborolan-2-yl)benzenesulfonamide (106 mg, crude), K3PO4 (143 mg, 675 umol, 3 eq), Pd(OAc)2 (5 mg, 23 umol, 0.1 eq) and bis(l-adamantyl)-butylphosphane (8 mg, 23 umol, 0.1 eq) in n-BuOH (2 mL) was degassed and purged with N2 3 times, and then the mixture was stirred at 50 C for 16 hours under N2 atmosphere. On completion, the mixture was diluted with ethyl acetate (20 mL) and water (30 mL). The mixture was extracted with ethyl acetate (2 x 30 mL). The combined organic layer was washed with water (30 mL) and brine (2 x 30 mL), dried over Na2S04 and concentrated in vacuo. The residue was purified by prep-HPLC. The eluent was concentrated to remove organic solvent, and the aqueous solution was lyophilized to give the title compound (33.6 mg, 30% yield) as a white solid. The title compound was confirmed by 1H NMR and LCMS.
  • 3
  • [ 486422-05-3 ]
  • tert-butyl 3-bromo-2-methyl-1H-indole-1-carboxylate [ No CAS ]
  • C22H26N2O4S [ No CAS ]
  • 4
  • [ 486422-05-3 ]
  • C14H15BrClNO2 [ No CAS ]
  • C22H25ClN2O4S [ No CAS ]
  • 5
  • [ 486422-05-3 ]
  • C14H16BrNO3 [ No CAS ]
  • C22H26N2O5S [ No CAS ]
  • 6
  • [ 486422-05-3 ]
  • C15H18BrNO3 [ No CAS ]
  • C23H28N2O5S [ No CAS ]
  • 7
  • [ 486422-05-3 ]
  • C15H19BrN2O4S [ No CAS ]
  • C23H29N3O6S2 [ No CAS ]
  • 8
  • [ 486422-05-3 ]
  • C15H18BrNO4S [ No CAS ]
  • C23H28N2O6S2 [ No CAS ]
  • 9
  • [ 486422-05-3 ]
  • C17H20BrNO4 [ No CAS ]
  • C25H30N2O6S [ No CAS ]
  • 10
  • [ 486422-05-3 ]
  • C17H20BrNO4 [ No CAS ]
  • C25H30N2O6S [ No CAS ]
  • 11
  • [ 486422-05-3 ]
  • C15H15BrN2O2 [ No CAS ]
  • C23H25N3O4S [ No CAS ]
  • 12
  • [ 486422-05-3 ]
  • 1-tert-butyl 5-ethyl 3-bromo-2-methyl-1H-indole-1,5-dicarboxylate [ No CAS ]
  • C25H30N2O6S [ No CAS ]
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 486422-05-3 ]

Organoboron

Chemical Structure| 486422-04-2

[ 486422-04-2 ]

N,N-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.99

Chemical Structure| 1293987-69-5

[ 1293987-69-5 ]

N-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.95

Chemical Structure| 1073353-47-5

[ 1073353-47-5 ]

N-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.94

Chemical Structure| 486422-06-4

[ 486422-06-4 ]

N,N-Dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.92

Chemical Structure| 911228-95-0

[ 911228-95-0 ]

N,N-Diethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide

Similarity: 0.91

Aryls

Chemical Structure| 486422-04-2

[ 486422-04-2 ]

N,N-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.99

Chemical Structure| 1293987-69-5

[ 1293987-69-5 ]

N-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.95

Chemical Structure| 1073353-47-5

[ 1073353-47-5 ]

N-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.94

Chemical Structure| 486422-06-4

[ 486422-06-4 ]

N,N-Dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.92

Chemical Structure| 911228-95-0

[ 911228-95-0 ]

N,N-Diethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide

Similarity: 0.91

Amines

Chemical Structure| 486422-04-2

[ 486422-04-2 ]

N,N-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.99

Chemical Structure| 1293987-69-5

[ 1293987-69-5 ]

N-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.95

Chemical Structure| 1073353-47-5

[ 1073353-47-5 ]

N-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.94

Chemical Structure| 486422-06-4

[ 486422-06-4 ]

N,N-Dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.92

Chemical Structure| 911228-95-0

[ 911228-95-0 ]

N,N-Diethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide

Similarity: 0.91

Sulfamides

Chemical Structure| 486422-04-2

[ 486422-04-2 ]

N,N-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.99

Chemical Structure| 1293987-69-5

[ 1293987-69-5 ]

N-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.95

Chemical Structure| 1073353-47-5

[ 1073353-47-5 ]

N-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.94

Chemical Structure| 486422-06-4

[ 486422-06-4 ]

N,N-Dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

Similarity: 0.92

Chemical Structure| 911228-95-0

[ 911228-95-0 ]

N,N-Diethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide

Similarity: 0.91

; ;