[ CAS No. 35963-20-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}

Cat. No.: {[proInfo.prAm]}

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type	HazMat fee for 500 gram (Estimated)
Excepted Quantity	USD 0.00
Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

2D 3D

Structure of 35963-20-3 * Storage: {[proInfo.prStorage]}

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	Inquiry	{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price) ]}	{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price) ]}	{[ item.pr_usastock ]}		{[ item.pr_chinastock ]}	{[ item.pr_remark ]}	Login		Inquiry

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

For Research Only 120K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 35963-20-3 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 35963-20-3 ]

SDS Specification

Alternatived Products of [ 35963-20-3 ]

Product Details of [ 35963-20-3 ]

CAS No. :	35963-20-3	MDL No. :	MFCD00064158
Formula :	C₁₀H₁₆O₄S	Boiling Point :	-
Linear Structure Formula :	HO₃SCH₂C₇H₇(CH₃)₂O	InChI Key :	MIOPJNTWMNEORI-XVKPBYJWSA-N
M.W :	232.30	Pubchem ID :	5771688
Synonyms :		Chemical Name :	((1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid

Safety of [ 35963-20-3 ]

Signal Word:	Danger	Class:	8
Precautionary Statements:	P501-P260-P264-P280-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P405	UN#:	3261
Hazard Statements:	H314	Packing Group:	Ⅱ
GHS Pictogram:

Application In Synthesis of [ 35963-20-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 35963-20-3 ]
Downstream synthetic route of [ 35963-20-3 ]

[ 35963-20-3 ] Synthesis Path-Upstream 1~1

1
[ 35963-20-3 ]
[ 107869-45-4 ]

Reference： [1] Organic Letters, 2000, vol. 2, # 26, p. 4157 - 4160
[2] Journal of the American Chemical Society, 1988, vol. 110, p. 8477
[3] Tetrahedron, 1986, vol. 42, # 14, p. 4035 - 4044
[4] Organic Process Research and Development, 2005, vol. 9, # 2, p. 193 - 197
[5] Organic Syntheses, 1990, vol. 69, p. 158 - 158

[ 35963-20-3 ] Synthesis Path-Downstream 1~3

1
[ 35963-20-3 ]
[ 21286-54-4 ]

Yield	Reaction Conditions	Operation in experiment
	With thionyl chloride; for 12h;Reflux;	General procedure: (1S)-(+)-Camphor-10-sulfonic acid (1.16 g, 5 mmol) was refluxed in thionyl chloride (8 mL) for 12 h. Then, the excess thionyl chloride was removed under reduced pressure to afford (1S)-(+)-10-camphorsulfonyl chloride, which was used in the next step without purification.

Reference： [1]Tetrahedron,1986,vol. 42,p. 4035 - 4044
[2]Bulletin of the Chemical Society of Japan,1981,vol. 54,p. 2712 - 2723
[3]Bulletin of the Chemical Society of Japan,1983,vol. 56,p. 3802 - 3812
[4]Bulletin de la Societe Chimique de France,1976,p. 862 - 866
[5]Chemische Berichte,1997,vol. 130,p. 879 - 885
[6]Organic Letters,2000,vol. 2,p. 4157 - 4160
[7]Tetrahedron Asymmetry,2011,vol. 22,p. 722 - 727
[8]Chemical Communications,2012,vol. 48,p. 4630 - 4632
[9]Organic Process Research and Development,2005,vol. 9,p. 193 - 197
[10]Organic Syntheses,1990,vol. 69,p. 158 - 158

2
[ 35963-20-3 ]
[ 105601-04-5 ]
(S)-3-[1-(dimethylamino)ethyl]phenol (1S)-10-camphorsulfonate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
25.7 - 31.0%	In ethanol; ethyl acetate; at 5 - 70℃;	Preparation of S- (-)-3- (1-DIMETHYLAMINO) PHENOL (III) Resolving compound (IV) with an 1 equivalent amount OF S- (+)-CAMPHOR-10-SULFONIC acid A solution of compound (IV) in ethylacetate (0.505 mol) * in 500 ml of ethylacetate) is introduced into a 1-liter round flask with a magnetic stirrer and a solution OF S- (+)-CAMPHOR- 10-sulfonic acid (117.4 g (0.505 mol) IN 250 ml of anhydrous ethanol), prepared in warm conditions, is added. The solution is inoculated and left to stand in a refrigerator (+5 C) overnight. The precipitated crystals are sucked off through fritted glass and left to air dry overnight. 1) 82.2 g of white crystals with m. p. = 165-171 C are obtained, which are dissolved in 190 ml of absolute ethanol under reflux. 380 ml of ethylacetate are added under warm conditions and crystallization is performed according to the above-mentioned procedure. 2) 64.1 g of white crystals with m. p. = 174-176 C are obtained, which are dissolved in 150 ML OF ETHANOL (ABSOL. ) UNDER REFLUX AND 300 ML OF ETHYLACETATE ARE ADDED UNDER WARM conditions. 3) 56.5 g of white crystals with m. p. = 177-179 C are obtained, which are dissolved in 130 ML OF ETHANOL (ABSOL. ) UNDER REFLUX AND 260 ML OF ETHYLACETATE ARE ADDED UNDER WARM conditions. 4) 51.6 g of white crystals with m. p. = 179-181 C are obtained; i. e. 25.7 % of the theoretical amount. * the contents of compound (IV) was determined by titration Resolving compound (IV) with 0.6 equivalent amount OF S- (+)-CAMPHOR-10-SULFONIC acid 100 g (0.605 mol) of compound (IV) are dissolved in 600 ml of ethylacetate under stirring and reflux. A solution of S- (+)-CAMPHOR-10-SULFONIC acid (84.3 g (0.363 mol) in 125 ML of anhydrous ethanol) is added under stirring at 70 C. The solution is inoculated, left to cool down to room temperature under stirring, cooled down with brine to-10 up TO-15C and it is left to crystallize for at least 12 hours under exclusion of air humidity. The precipitated first fraction of crystals is sucked off and air dried. 1) 95.0 g of white crystals with m. p. =173-175 C are obtained, which are dissolved in 175 ml of ethanol under stirring and reflux and 350 ml of ethylacetate are added at a temperature of the solution between 60-70 C. The CAMPHORSULFONATE will start to crystallize and is left to crystallize at a temperature-5 up to-10 C for at least 12 hours. The precipitated fraction is sucked off, washed with 2x 50 ml of ethylacetate and air dried. 2) 79.5 g of the second fraction with m. p. 176-178 C are obtained, which are again recrystallized in a mixture of ethanol: ethylacetate (150 ML : 300 ml) following the above specified procedure. After being washed with 2x 50 ml of ethylacetate, the product is dried freely. 3) 74.6 g of the third fraction with m. p. =177-179 C are obtained; i. e. 31.0 % of the theoretical yield.

Reference： [1]Patent: WO2004/37771,2004,A1 .Location in patent: Page 10, 11

3
[ 188416-20-8 ]
[ 35963-20-3 ]
[ 137234-62-9 ]

Yield	Reaction Conditions	Operation in experiment
		Preparation of Voriconazole Camphorsulfonate (wet) from Hydrochloride Salt of (2R,3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. Hydrochloride salt of (2R,3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (180 gm) obtained from Step III of Example 1 or Example 2 or Example 3 was added to methanol (720 mL) at 20 C.-25 C. followed by pH adjustment (8.0-9.0) with 40% w/v aqueous sodium hydroxide solution (50 mL) under nitrogen blanketing. To this reaction mixture, ammonium formate (108.2 gm) was added followed by addition of wet palladium/carbon [Pd/C (2.5% w/w dry, 18 gm)] treated with de-ionized water. The reaction mixture was further heated and stirred at 55 C.-60 C. followed by cooling of the mixture to 30 C.-35 C. The reaction mixture was filtered through hyflobed and washed with methanol (360 mL) first and then with a mixture of de-ionized water (1800 mL) and dichloromethane (900 mL) at 15 C.-20 C. followed by stirring. To the organic layer, de-ionized water (360 mL) was added followed by pH adjustment with 2N hydrochloric acid solution (6 mL) at the same temperature. The solvent was recovered under reduced pressure at 40 C.-45 C. to give residual solid. To the residue acetone (2700 mL) was added followed by addition of the methanolic solution of (1R)-(-)-10-camphorsulfonic acid (99.5 gm in 900 mL methanol) at 40 C.-45 C. Seed of voriconazole camphorsulfonate (0.18 gm) was added to the reaction mixture and the mixture stirred at 40 C.-45 C. for 60 minutes. The slurry so obtained was cooled to 30 C.-35 C. followed by further cooling to 20 C.-25 C. The mixture was stirred for 10-12 hours at 20 C.-25 C. followed by filtration and washing with acetone (180 mL) to give wet voriconazole camphorsulfonate. Wet wt: 91 gm. Voriconazole camphorsulfonate (wet) (entire quantity from Step 4A of Example 4) was added to a stirred mixture of de-ionized water (360 mL) and dichloromethane (360 mL) at 15 C.-25 C. followed by pH adjustment of the mixture to pH 10-11 with 40% w/v aqueous sodium hydroxide solution (16.2 mL). The organic layer was washed with de-ionized water (360 mL) followed by filtration of organic layer through 0.45 micron filter. The filtered layer was further washed with dichloromethane (90 mL) and solvent was recovered under reduced pressure (50-500 torr) at 35 C.-45 C. to give a residual solid. Isopropyl alcohol (450 mL) was added to the residue followed by heating and stirring of the mixture at 60 C.-70 C. until the mixture was dissolved, followed by recovery of isopropyl alcohol under reduced pressure (50-500 torr) at 50 C.-60 C. to obtain a residual volume of 270 mL. The concentrated solution so obtained was heated to 60 C.-70 C. followed by cooling of the solution to 45 C.-50 C. The solution was further cooled to 5 C.-10 C. followed by stirring for 60 minutes at the same temperature. The solid obtained was filtered and washed with isopropyl alcohol (135 mL) followed by drying of the solid under reduced pressure at 50 C.-55 C. until constant weight. %Yield: 42.8%

Reference： [1]Patent: US2014/350252,2014,A1 .Location in patent: Paragraph 0045; 0046; 0047; 0048

Recommend Products

Same Skeleton Products

Related Products

Isomers

Technical Information

? Baeyer-Villiger Oxidation ? Barbier Coupling Reaction ? Baylis-Hillman Reaction ? Bucherer-Bergs Reaction ? Clemmensen Reduction ? Corey-Bakshi-Shibata (CBS) Reduction ? Corey-Chaykovsky Reaction ? Fischer Indole Synthesis ? Grignard Reaction ? Halogenation ? Heat of Combustion ? Henry Nitroaldol Reaction ? Horner-Wadsworth-Emmons Reaction ? Hydride Reductions ? Lawesson's Reagent ? Leuckart-Wallach Reaction ? McMurry Coupling ? Meerwein-Ponndorf-Verley Reduction ? Oxidation States of Sulfur Compounds ? Passerini Reaction ? Paternò-Büchi Reaction ? Petasis Reaction ? Peterson Olefination ? Pictet-Spengler Tetrahydroisoquinoline Synthesis ? Preparation of Aldehydes and Ketones ? Preparation of Amines ? Prins Reaction ? Reactions of Aldehydes and Ketones ? Reactions of Amines ? Reformatsky Reaction ? Robinson Annulation ? Schlosser Modification of the Wittig Reaction ? Schmidt Reaction ? Specialized Acylation Reagents-Ketenes ? Stobbe Condensation ? Tebbe Olefination ? Ugi Reaction ? Wittig Reaction ? Wolff-Kishner Reduction

Historical Records

Similar Product of
[ 35963-20-3 ]

A644249[ 3144-16-9 ]

((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid

Reason: Optical isomers

Related Functional Groups of
[ 35963-20-3 ]

Aliphatic Cyclic Hydrocarbons

[ 5872-08-2 ]

(7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid

Similarity: 1.00

[ 209736-59-4 ]

((1S,3S,4S)-3-Bromo-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid hydrate

Similarity: 0.78

[ 14575-84-9 ]

Ammonium ((1R,3S,4S,7R)-3-bromo-1,7-dimethyl-2-oxobicyclo[2.2.1]heptan-7-yl)methanesulfonate

Similarity: 0.75

[ 55870-50-3 ]

Ammonium ((1S,3R,4R,7S)-3-bromo-1,7-dimethyl-2-oxobicyclo[2.2.1]heptan-7-yl)methanesulfonate

Similarity: 0.75

Sulfonic Acids

[ 5872-08-2 ]

(7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid

Similarity: 1.00

[ 209736-59-4 ]

((1S,3S,4S)-3-Bromo-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid hydrate

Similarity: 0.78

[ 1588441-14-8 ]

Butane-1,4-disulfonic acid hydrate

Similarity: 0.67

[ 26978-64-3 ]

4-Hydroxybutane-1-sulfonic acid

Similarity: 0.62

[ 3687-18-1 ]

3-Aminopropane-1-sulfonic acid

Similarity: 0.55

Ketones

[ 5872-08-2 ]

(7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid

Similarity: 1.00

[ 209736-59-4 ]

((1S,3S,4S)-3-Bromo-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid hydrate

Similarity: 0.78

[ 14575-84-9 ]

Ammonium ((1R,3S,4S,7R)-3-bromo-1,7-dimethyl-2-oxobicyclo[2.2.1]heptan-7-yl)methanesulfonate

Similarity: 0.75

[ 55870-50-3 ]

Ammonium ((1S,3R,4R,7S)-3-bromo-1,7-dimethyl-2-oxobicyclo[2.2.1]heptan-7-yl)methanesulfonate

Similarity: 0.75

[ 90458-75-6 ]

Sodium ((1,4-phenylenebis(methanylylidene))bis(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl-3-ylidene))dimethanesulfonate

Similarity: 0.68

Ghs Precautionary Statements

Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

[ CAS No. 35963-20-3 ] {[proInfo.proName]}

Quality Control of [ 35963-20-3 ]

Related Doc. of [ 35963-20-3 ]

Product Details of [ 35963-20-3 ]

Safety of [ 35963-20-3 ]

Application In Synthesis of [ 35963-20-3 ]

[ 35963-20-3 ] Synthesis Path-Upstream 1~1

[ 35963-20-3 ] Synthesis Path-Downstream 1~3

Technical Information

Similar Product of [ 35963-20-3 ]

Related Functional Groups of [ 35963-20-3 ]

Aliphatic Cyclic Hydrocarbons

Sulfonic Acids

Ketones

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Similar Product of
[ 35963-20-3 ]

Related Functional Groups of
[ 35963-20-3 ]