天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Home Cart 0 Sign in  

[ CAS No. 35320-23-1 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 35320-23-1
Chemical Structure| 35320-23-1
Structure of 35320-23-1 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 35320-23-1 ]

Related Doc. of [ 35320-23-1 ]

Alternatived Products of [ 35320-23-1 ]
Product Citations

Product Details of [ 35320-23-1 ]

CAS No. :35320-23-1 MDL No. :MFCD00064413
Formula : C3H9NO Boiling Point : -
Linear Structure Formula :CH3CH(NH2)CH2OH InChI Key :-
M.W : 75.11 Pubchem ID :-
Synonyms :
Chemical Name :(R)-2-Aminopropan-1-ol

Calculated chemistry of [ 35320-23-1 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 5
Num. arom. heavy atoms : 0
Fraction Csp3 : 1.0
Num. rotatable bonds : 1
Num. H-bond acceptors : 2.0
Num. H-bond donors : 2.0
Molar Refractivity : 20.4
TPSA : 46.25 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : No
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -7.45 cm/s

Lipophilicity

Log Po/w (iLOGP) : 0.97
Log Po/w (XLOGP3) : -0.97
Log Po/w (WLOGP) : -0.67
Log Po/w (MLOGP) : -0.63
Log Po/w (SILICOS-IT) : -0.78
Consensus Log Po/w : -0.42

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 2.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : 0.37
Solubility : 177.0 mg/ml ; 2.35 mol/l
Class : Highly soluble
Log S (Ali) : 0.48
Solubility : 229.0 mg/ml ; 3.05 mol/l
Class : Highly soluble
Log S (SILICOS-IT) : 0.34
Solubility : 166.0 mg/ml ; 2.21 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.0

Safety of [ 35320-23-1 ]

Signal Word:Danger Class:8
Precautionary Statements:P280-P305+P351+P338-P310 UN#:2735
Hazard Statements:H314 Packing Group:Ⅱ
GHS Pictogram:

Application In Synthesis of [ 35320-23-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 35320-23-1 ]

[ 35320-23-1 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 35320-23-1 ]
  • [ 542-58-5 ]
  • [ 119844-67-6 ]
YieldReaction ConditionsOperation in experiment
26%
Stage #1: With sodium hydride In tetrahydrofuran at 20℃; for 0.583333 h;
Stage #2: at 20℃; for 18 h; Heating / reflux		 1) (5R)-5-Methyl-3-morpholinone Sodium hydride (55percent, 0.820 g) was added to a solution of (2R)-2-amino-1-propanol (1.33 mL) in tetrahydrofuran (200 mL) at room temperature, and the resultant mixture was stirred for 35 minutes. Chloroethyl acetate (1.80 mL) was added to the reaction solution over 5 minutes at room temperature, and the mixture was stirred for 25 minutes, and then heated to reflux for 17.5 hours. After air cooling, the reaction solution was filtered, and a residue obtained by evaporating the solvent of the filtrate under reduced pressure was purified by silica gel column chromatography (ethyl acetate-n-hexane), to obtain a crude product of (5R)-5-methyl-3-morpholinone (0.520 g, 26percent) as an oily product.
Reference： [1] Patent: EP1785418, 2007, A1, . Location in patent: Page/Page column 149
  • 2
  • [ 35320-23-1 ]
  • [ 105-39-5 ]
  • [ 119844-67-6 ]
Reference： [1] ACS Combinatorial Science, 2016, vol. 18, # 9, p. 569 - 574
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 35320-23-1 ]

Amino Acid Derivatives

Chemical Structure| 22724-81-8

[ 22724-81-8 ]

(S)-2-Aminopentan-1-ol

Similarity: 0.67

Chemical Structure| 2026-48-4

[ 2026-48-4 ]

(S)-2-Amino-3-methylbutan-1-ol

Similarity: 0.63

Chemical Structure| 4276-09-9

[ 4276-09-9 ]

D-Valinol

Similarity: 0.63

Chemical Structure| 16369-05-4

[ 16369-05-4 ]

2-Amino-3-methylbutan-1-ol

Similarity: 0.63

Chemical Structure| 53448-09-2

[ 53448-09-2 ]

(R)-2-Amino-4-methylpentan-1-ol

Similarity: 0.60

; ;