Alternatived Products of [ 2956-58-3 ]
Product Details of [ 2956-58-3 ]
CAS No. : | 2956-58-3 |
MDL No. : | MFCD00042935 |
Formula : |
C8H12N2O2
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | AYGYHGXUJBFUJU-UHFFFAOYSA-N |
M.W : |
168.19
|
Pubchem ID : | 168964 |
Synonyms : |
|
Calculated chemistry of [ 2956-58-3 ] Expand+
Physicochemical Properties
Num. heavy atoms : |
12 |
Num. arom. heavy atoms : |
0 |
Fraction Csp3 : |
0.25 |
Num. rotatable bonds : |
7 |
Num. H-bond acceptors : |
2.0 |
Num. H-bond donors : |
2.0 |
Molar Refractivity : |
45.63 |
TPSA : |
58.2 ?2 |
Pharmacokinetics
GI absorption : |
High |
BBB permeant : |
No |
P-gp substrate : |
No |
CYP1A2 inhibitor : |
No |
CYP2C19 inhibitor : |
No |
CYP2C9 inhibitor : |
No |
CYP2D6 inhibitor : |
No |
CYP3A4 inhibitor : |
No |
Log Kp (skin permeation) : |
-7.3 cm/s |
Lipophilicity
Log Po/w (iLOGP) : |
1.43 |
Log Po/w (XLOGP3) : |
0.04 |
Log Po/w (WLOGP) : |
-0.41 |
Log Po/w (MLOGP) : |
-0.07 |
Log Po/w (SILICOS-IT) : |
0.52 |
Consensus Log Po/w : |
0.3 |
Druglikeness
Lipinski : |
0.0 |
Ghose : |
None |
Veber : |
0.0 |
Egan : |
0.0 |
Muegge : |
1.0 |
Bioavailability Score : |
0.55 |
Water Solubility
Log S (ESOL) : |
-0.45 |
Solubility : |
60.2 mg/ml ; 0.358 mol/l |
Class : |
Very soluble |
Log S (Ali) : |
-0.81 |
Solubility : |
25.8 mg/ml ; 0.153 mol/l |
Class : |
Very soluble |
Log S (SILICOS-IT) : |
-1.58 |
Solubility : |
4.46 mg/ml ; 0.0265 mol/l |
Class : |
Soluble |
Medicinal Chemistry
PAINS : |
0.0 alert |
Brenk : |
1.0 alert |
Leadlikeness : |
1.0 |
Synthetic accessibility : |
1.68 |