天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Home Cart 0 Sign in  

[ CAS No. 2915-53-9 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 2915-53-9
Chemical Structure| 2915-53-9
Structure of 2915-53-9 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 2915-53-9 ]

Related Doc. of [ 2915-53-9 ]

Alternatived Products of [ 2915-53-9 ]
Product Citations

Product Details of [ 2915-53-9 ]

CAS No. :2915-53-9 MDL No. :MFCD00072705
Formula : C20H36O4 Boiling Point : -
Linear Structure Formula :- InChI Key :TVWTZAGVNBPXHU-NXVVXOECSA-N
M.W : 340.50 Pubchem ID :6433353
Synonyms :

Calculated chemistry of [ 2915-53-9 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 24
Num. arom. heavy atoms : 0
Fraction Csp3 : 0.8
Num. rotatable bonds : 18
Num. H-bond acceptors : 4.0
Num. H-bond donors : 0.0
Molar Refractivity : 100.35
TPSA : 52.6 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -3.38 cm/s

Lipophilicity

Log Po/w (iLOGP) : 4.83
Log Po/w (XLOGP3) : 7.04
Log Po/w (WLOGP) : 5.35
Log Po/w (MLOGP) : 4.01
Log Po/w (SILICOS-IT) : 6.15
Consensus Log Po/w : 5.48

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 1.0
Egan : 0.0
Muegge : 2.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -5.2
Solubility : 0.00216 mg/ml ; 0.00000633 mol/l
Class : Moderately soluble
Log S (Ali) : -7.96
Solubility : 0.00000372 mg/ml ; 0.0000000109 mol/l
Class : Poorly soluble
Log S (SILICOS-IT) : -5.76
Solubility : 0.000596 mg/ml ; 0.00000175 mol/l
Class : Moderately soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 2.0 alert
Leadlikeness : 2.0
Synthetic accessibility : 3.57

Safety of [ 2915-53-9 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 2915-53-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2915-53-9 ]

[ 2915-53-9 ] Synthesis Path-Downstream   1~14

  • 1
  • [ 2915-53-9 ]
  • [ 141-43-5 ]
  • [ 54046-34-3 ]
  • 2
  • [ 2915-53-9 ]
  • [ 67-63-0 ]
  • [ 77666-63-8 ]
  • diaterebic acid dioctylester [ No CAS ]
  • [ 77666-67-2 ]
  • 3
  • [ 112-35-6 ]
  • [ 2370-71-0 ]
  • [ 2915-53-9 ]
  • (Z)-But-2-enedioic acid 2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl ester octyl ester [ No CAS ]
  • 4
  • [ 108-31-6 ]
  • [ 111-87-5 ]
  • [ 2370-71-0 ]
  • [ 2915-53-9 ]
  • 9
  • [ 111-87-5 ]
  • octyloctanoate [ No CAS ]
  • [ 2915-53-9 ]
  • 10
  • [ 311-28-4 ]
  • [ 110-17-8 ]
  • [ 2915-53-9 ]
YieldReaction ConditionsOperation in experiment
With potassium hydroxide; In chloroform; 1-bromo-hexane; water; Petroleum ether; (ii) Preparation of Hexyl/Octyl Maleate/Fumarate Monooctyl maleic/fumaric acid (88 g, 0.39 mole) was dissolved in chloroform (200 ml) and was stirred in a 1 L Erlenmeyer (Quick Fit) flask, fitted with condenser, with a solution of potassium hydroxide (21 g, 0.38 mole) and tetrabutyl ammonium iodide (15 g, 0.04 mole) in 200 mls of water. To the stirred mixture was added hexyl bromide 64 g, 0.39 mole) and the two phase mixture was stirred rapidly under reflux for 5 hours. The chloroform layer was separated off, washed with sodium carbonate solution, then with water, and then dried over sodium sulphate. After filtering and evaporating the resulting oil was treated with 30/40 petroleum ether which precipitated the catalyst which could be reused. Filtration/evaporation yielded the crude product as an oil (77 g). Distillation in vacuo removed 13.1 g hexyl bromide. The yield of undistilled material was 59.3 g (62percent based on hexyl bromide).
  • 11
  • sodium metabisulfite [ No CAS ]
  • [ 2915-53-9 ]
  • [ 2373-23-1 ]
YieldReaction ConditionsOperation in experiment
In water; (iii) Preparation of Hexyl/Octyl Sulphosuccinate Hexyl/octyl maleate/fumarate (50 g, 0.16 mole) was dissolved in methylated spirit (100 ml) and the pH of the mixture was adjusted to about 7.5 with sodium carbonate. The mixture was stirred under reflux for 5 hours with a solution of sodium metabisulphite (60 g) in water (160 ml) in a 3-necked round bottom flask fitted with stirrer and condenser. The hot solution was filtered and set to crystallise. The crude crystals were filtered off, dried and extracted with boiling ethanol. The residual inorganics were filtered off. Evaporation of the filtrate yielded the product as a glassy solid (20 g) which failed to recrystallise from acetone or ethanol. This material contained 92percent detergent-active material and 1.5percent non-detergent organic matter. It had infra-red peaks at 1735 cm-1 (C=O) and 1210-1240 cm-1 (SO3 Na) and was also identified by 1 H NMR.
  • 12
  • [ 2915-53-9 ]
  • [ 14814-09-6 ]
  • C29H58O7SSi [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium tert-butylate; In toluene; at 0 - 20℃; for 1.0h; Example 21; Preparation of compound 190; To a suspension of 20 mg (0.17 mmol) of potassium tert-butanolate in 40 ml of dry toluene is added dropwise under nitrogen at 0°C 4.13 g (17.3 mmol) of 3-mercapto-propyltriethoxysi- lane, followed by the dropwise addition of 5.89 g (17.3 mmol) of <strong>[2915-53-9]dioctyl maleate</strong>. The reaction mixture is stirred for one hour at room temperature. Water is then added and the product is extracted with ethyl acetate. The organic phase is washed with H2O, NaCI, dried over sodium sulfate, filtered and evaporated to dryness using a rotary evaporator to afford 9.80 g of compound 190 as colourless liquid. 1H-NMR (300 MHz, CDCI3): delta = 4.20-4.00 (m, CO2CH2, 4H); 3.90-3.75 (m, SiOCH2, 6H); 3.70-3.60 (m, SCHCO2, 1 H); 3.10-2.95 (m, SCHCH2CO2, 1 H); 2.70-2.60 (m, SCHCH2CO2 + SCH2, 3H); 1.80-1.55 (m, SCH2CH2 + CO2CH2CH2, 6H); 1.55-1.15 (m, SiOCH2CH3 + CH2, 29H); 1.00-0.80 (m, CH3, 6H); 0.80-0.65 (m, SiCH2, 2H).
  • 13
  • [ 108-31-6 ]
  • [ 111-87-5 ]
  • [ 2915-53-9 ]
  • [ 2997-85-5 ]
  • 14
  • [ 1073-31-0 ]
  • [ 2915-53-9 ]
  • [ 1553995-25-7 ]
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 2915-53-9 ]

Alkenyls

Chemical Structure| 105-76-0

[ 105-76-0 ]

Dibutyl maleate

Similarity: 0.96

Chemical Structure| 36840-85-4

[ 36840-85-4 ]

Pentane-1,5-diyl diacrylate

Similarity: 0.89

Chemical Structure| 2459-05-4

[ 2459-05-4 ]

(E)-4-Ethoxy-4-oxobut-2-enoic acid

Similarity: 0.86

Chemical Structure| 638-10-8

[ 638-10-8 ]

Ethyl 3-methylbut-2-enoate

Similarity: 0.83

Chemical Structure| 27829-72-7

[ 27829-72-7 ]

Ethyl (E)-hex-2-enoate

Similarity: 0.81

Aliphatic Chain Hydrocarbons

Chemical Structure| 105-76-0

[ 105-76-0 ]

Dibutyl maleate

Similarity: 0.96

Chemical Structure| 36840-85-4

[ 36840-85-4 ]

Pentane-1,5-diyl diacrylate

Similarity: 0.89

Chemical Structure| 2459-05-4

[ 2459-05-4 ]

(E)-4-Ethoxy-4-oxobut-2-enoic acid

Similarity: 0.86

Chemical Structure| 638-10-8

[ 638-10-8 ]

Ethyl 3-methylbut-2-enoate

Similarity: 0.83

Chemical Structure| 27829-72-7

[ 27829-72-7 ]

Ethyl (E)-hex-2-enoate

Similarity: 0.81

Esters

Chemical Structure| 105-76-0

[ 105-76-0 ]

Dibutyl maleate

Similarity: 0.96

Chemical Structure| 36840-85-4

[ 36840-85-4 ]

Pentane-1,5-diyl diacrylate

Similarity: 0.89

Chemical Structure| 2459-05-4

[ 2459-05-4 ]

(E)-4-Ethoxy-4-oxobut-2-enoic acid

Similarity: 0.86

Chemical Structure| 638-10-8

[ 638-10-8 ]

Ethyl 3-methylbut-2-enoate

Similarity: 0.83

Chemical Structure| 497-23-4

[ 497-23-4 ]

Furan-2(5H)-one

Similarity: 0.83

; ;