天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Home Cart 0 Sign in  

[ CAS No. 2508-29-4 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 2508-29-4
Chemical Structure| 2508-29-4
Structure of 2508-29-4 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 2508-29-4 ]

Related Doc. of [ 2508-29-4 ]

Alternatived Products of [ 2508-29-4 ]
Product Citations

Product Details of [ 2508-29-4 ]

CAS No. :2508-29-4 MDL No. :MFCD00008237
Formula : C5H13NO Boiling Point : -
Linear Structure Formula :H2NCH2CH2CH2CH2CH2OH InChI Key :LQGKDMHENBFVRC-UHFFFAOYSA-N
M.W : 103.16 Pubchem ID :75634
Synonyms :

Calculated chemistry of [ 2508-29-4 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 7
Num. arom. heavy atoms : 0
Fraction Csp3 : 1.0
Num. rotatable bonds : 4
Num. H-bond acceptors : 2.0
Num. H-bond donors : 2.0
Molar Refractivity : 30.02
TPSA : 46.25 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : No
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -7.16 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.42
Log Po/w (XLOGP3) : -0.33
Log Po/w (WLOGP) : 0.11
Log Po/w (MLOGP) : 0.23
Log Po/w (SILICOS-IT) : 0.13
Consensus Log Po/w : 0.31

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -0.01
Solubility : 101.0 mg/ml ; 0.982 mol/l
Class : Very soluble
Log S (Ali) : -0.18
Solubility : 68.2 mg/ml ; 0.661 mol/l
Class : Very soluble
Log S (SILICOS-IT) : -0.9
Solubility : 13.1 mg/ml ; 0.127 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.0

Safety of [ 2508-29-4 ]

Signal Word:Danger Class:8
Precautionary Statements:P261-P280-P305+P351+P338-P310 UN#:2735
Hazard Statements:H302-H314 Packing Group:Ⅲ
GHS Pictogram:

Application In Synthesis of [ 2508-29-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2508-29-4 ]

[ 2508-29-4 ] Synthesis Path-Downstream   1~8

  • 1
  • [ 2508-29-4 ]
  • [ 1655-06-7 ]
  • (1R,2R)-2-Hydroxy-cyclohexanecarboxylic acid (5-hydroxy-pentyl)-amide [ No CAS ]
  • (1R,2R)-2-Hydroxy-cyclohexanecarboxylic acid 5-amino-pentyl ester [ No CAS ]
  • 2
  • [ 75-29-6 ]
  • [ 2508-29-4 ]
  • [ 40447-21-0 ]
  • 3
  • [ 2508-29-4 ]
  • [ 51146-57-7 ]
  • <i>N</i>-(5-hydroxy-pentyl)-2-(4-isobutyl-phenyl)-propionamide [ No CAS ]
  • 4
  • [ 38222-83-2 ]
  • [ 2508-29-4 ]
  • [ 22509-74-6 ]
  • [ 63273-48-3 ]
  • [ 149831-83-4 ]
YieldReaction ConditionsOperation in experiment
With trifluoromethylsulfonic anhydride; In dichloromethane; benzene; A. 5-Phthalimido-1-pentyl triflate (15). To a solution of 5-aminopentanol (42.7 mmol) in benzene (100 mL) is added N-carbethoxyphthalimide (10.3 g, 47.0 mmol). The solution is stirred at room temperature for 5 h. The solvent is removed in vacuo to provide an oil, which is purified by flash chromatography. To a solution of 5-phthalimido-1-pentanol (22.2 mmol) in dry dichloromethane (50 mL) is added <strong>[38222-83-2]2,6-di-tert-butyl-4-methylpyridine</strong> (4.6 g, 22.2 mmol) and triflic anhydride (3.7 mL, 22.2 mmol) at 0° C. The reaction is stirred at room temperature for 20 min, poured into water, and extracted with dichloromethane. The combined extracts are dried over anhydrous sodium sulfate and concentrated in vacuo and to afford 5-phthalimido-1-pentyl triflate (15) which is used without further purification.
  • 5
  • [ 38222-83-2 ]
  • [ 2508-29-4 ]
  • [ 40447-15-2 ]
  • 5-acetamido-1-pentyl triflate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With trifluoromethylsulfonic anhydride; acetic anhydride; triethylamine; In methanol; dichloromethane; A. 5-Acetamido-1-pentyl triflate (30). A solution of 5-amino-1-pentanol (0.650 g, 6.31 mmol) in methanol (15 mL) is cooled to 0° C. and treated with triethylamine (1.62 mL, 11.6 mmol) followed by acetic anhydride (0.891 mL, 9.45 mmol). The reaction mixture is stirred at room temperature overnight. Additional triethylamine (1.6 mL, 11.6 mmol) and acetic anhydride (0.9 mL, 9.5 mmol) is added at room temperature and the solution is stirred 16 h further. Concentration in vacuo and flash chromatography affords 5-acetamido-1-pentanol. To a solution of 5-acetamido-1-pentanol (22.2 mmol) in dry dichloromethane (50 mL) is added <strong>[38222-83-2]2,6-di-tert-butyl-4-methylpyridine</strong> (4.6 g, 22.2 mmol) and triflic anhydride (3.7 mL, 22.2 mmol) at 0° C. The reaction is stirred at room temperature for 20 min, poured into water, and extracted with dichloromethane. The combined extracts are dried over anhydrous sodium sulfate and concentrated in vacuo and to afford 5-acetamido-1-pentyl triflate (30) which is used without further purification.
  • 6
  • [ 2508-29-4 ]
  • [ 78078-92-9 ]
  • [ 1234567-19-1 ]
  • 7
  • [ 2508-29-4 ]
  • [ 100-51-6 ]
  • [ 2905-56-8 ]
  • 8
  • [ 2508-29-4 ]
  • [ 1426827-79-3 ]
  • C16H25NO3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
81% With triethylamine; In dichloromethane; at 20℃; for 1.5h; To a solution of 51 (430 mg, 1.48 mmol) in DCM (20 mL) was added a solution of 5-aminopentan-1-ol 55 (152 mg, 1.47 mmol) in DCM (4 mL) and Et3N (619 1iL, 449 mg,4.44 mmol). The mixture was stirred for 1.5 h at rt after which a saturated aqueoussolution of NaHCO3 was added (40 mL). After separation, the organic layer was dried (Na2SO4) and concentrated. The residue was purified by gradient column chromatography (EtOAc/heptane 1/1 -f 3/1). The product 56 was obtained as a colorless sticky liquid (356 mg, 1.27 mmol, 8 1%). ‘H NIVIR (400 IVIFIz, CDC13) (ppm) 4.68 (s,1H), 4.14 (d, J= 8.0 Hz, 2H), 3.65 (dd, J= 11.7, 6.3 Hz, 2H), 3.19 (dd, J 13.2, 6.7 Hz,2H), 2.35-2.15 (m, 6H), 1.66 - 1.30 (m, 7H), 1.02-0.88 (m, 2H).
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 2508-29-4 ]

Aliphatic Chain Hydrocarbons

Chemical Structure| 67107-87-3

[ 67107-87-3 ]

12-Amino-1-dodecanol

Similarity: 1.00

Chemical Structure| 4048-33-3

[ 4048-33-3 ]

6-Aminohexan-1-ol

Similarity: 1.00

Chemical Structure| 19008-71-0

[ 19008-71-0 ]

8-Aminooctan-1-ol

Similarity: 1.00

Chemical Structure| 23160-46-5

[ 23160-46-5 ]

10-Aminodecan-1-ol

Similarity: 1.00

Chemical Structure| 13325-10-5

[ 13325-10-5 ]

4-Aminobutan-1-ol

Similarity: 0.93

Alcohols

Chemical Structure| 67107-87-3

[ 67107-87-3 ]

12-Amino-1-dodecanol

Similarity: 1.00

Chemical Structure| 4048-33-3

[ 4048-33-3 ]

6-Aminohexan-1-ol

Similarity: 1.00

Chemical Structure| 19008-71-0

[ 19008-71-0 ]

8-Aminooctan-1-ol

Similarity: 1.00

Chemical Structure| 23160-46-5

[ 23160-46-5 ]

10-Aminodecan-1-ol

Similarity: 1.00

Chemical Structure| 13325-10-5

[ 13325-10-5 ]

4-Aminobutan-1-ol

Similarity: 0.93

Amines

Chemical Structure| 67107-87-3

[ 67107-87-3 ]

12-Amino-1-dodecanol

Similarity: 1.00

Chemical Structure| 4048-33-3

[ 4048-33-3 ]

6-Aminohexan-1-ol

Similarity: 1.00

Chemical Structure| 19008-71-0

[ 19008-71-0 ]

8-Aminooctan-1-ol

Similarity: 1.00

Chemical Structure| 23160-46-5

[ 23160-46-5 ]

10-Aminodecan-1-ol

Similarity: 1.00

Chemical Structure| 13325-10-5

[ 13325-10-5 ]

4-Aminobutan-1-ol

Similarity: 0.93

; ;