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CAS No. : | 161420-87-7 | MDL No. : | MFCD00237017 |
Formula : | C19H20N2O4 | Boiling Point : | No data available |
Linear Structure Formula : | - | InChI Key : | ZZDRDGKSMGGBDI-KRWDZBQOSA-N |
M.W : | 340.37 | Pubchem ID : | 7019708 |
Synonyms : |
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Signal Word: | Warning | Class: | |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | |
Hazard Statements: | H315-H319-H335 | Packing Group: | |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
86.62% | With sodium hydroxide; In water; acetone; at 0 - 10℃; for 4h;pH 7.5 - 8; | B. The suspension 50g146 . 8nmol<strong>[161420-87-7]Fmoc-Dab-OH</strong> with 700 ml acetone: water = 1:in 1(v/v), in 0-10 °C add 38.4g176 . 1nmol (Boc)2O, 0.5NNaOH adjusting pH= 7.5-8, reaction 4 hours after Fmoc-Dab (Boc)-OH56g processing product, yield 86.62percent, HPLC99 . 4percent. The infrared, nuclear magnetic resonance confirmed correct structure, see Figure 3, Figure 4. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
86.5% | With [bis(acetoxy)iodo]benzene; In water; ethyl acetate; acetonitrile; at 20 - 30℃; for 72h; | A. The suspension 100g271 . 5nmolFmoc-Gln-OH with 2L ethyl acetate: acetonitrile: water = 2:1: mixed solution 1(v/v/v), in 20-30 C add 105.1g325 . 9nmolDipa, reaction 72 hours, post-processed to obtain product Fmoc-Dab-OH80g. Yield of 86.5%, HPLC: 99.6%. The infrared, nuclear magnetic resonance confirmed correct structure, see Figure 1, Figure 2. |
[ 201473-83-8 ]
(S)-2,4-Bis((((9H-fluoren-9-yl)methoxy)carbonyl)amino)butanoic acid
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