Alternatived Products of [ 1198-30-7 ]
Product Details of [ 1198-30-7 ]
CAS No. : | 1198-30-7 |
MDL No. : | MFCD00134166 |
Formula : |
C10H6N2
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | HJHXYSBRTVFEDD-UHFFFAOYSA-N |
M.W : |
154.17
|
Pubchem ID : | 306057 |
Synonyms : |
|
Calculated chemistry of [ 1198-30-7 ] Expand+
Physicochemical Properties
Num. heavy atoms : |
12 |
Num. arom. heavy atoms : |
10 |
Fraction Csp3 : |
0.0 |
Num. rotatable bonds : |
0 |
Num. H-bond acceptors : |
2.0 |
Num. H-bond donors : |
0.0 |
Molar Refractivity : |
46.46 |
TPSA : |
36.68 ?2 |
Pharmacokinetics
GI absorption : |
High |
BBB permeant : |
Yes |
P-gp substrate : |
No |
CYP1A2 inhibitor : |
Yes |
CYP2C19 inhibitor : |
No |
CYP2C9 inhibitor : |
No |
CYP2D6 inhibitor : |
No |
CYP3A4 inhibitor : |
No |
Log Kp (skin permeation) : |
-5.61 cm/s |
Lipophilicity
Log Po/w (iLOGP) : |
1.68 |
Log Po/w (XLOGP3) : |
2.3 |
Log Po/w (WLOGP) : |
2.11 |
Log Po/w (MLOGP) : |
0.87 |
Log Po/w (SILICOS-IT) : |
2.44 |
Consensus Log Po/w : |
1.88 |
Druglikeness
Lipinski : |
0.0 |
Ghose : |
None |
Veber : |
0.0 |
Egan : |
0.0 |
Muegge : |
1.0 |
Bioavailability Score : |
0.55 |
Water Solubility
Log S (ESOL) : |
-2.86 |
Solubility : |
0.212 mg/ml ; 0.00138 mol/l |
Class : |
Soluble |
Log S (Ali) : |
-2.71 |
Solubility : |
0.302 mg/ml ; 0.00196 mol/l |
Class : |
Soluble |
Log S (SILICOS-IT) : |
-3.77 |
Solubility : |
0.0261 mg/ml ; 0.000169 mol/l |
Class : |
Soluble |
Medicinal Chemistry
PAINS : |
0.0 alert |
Brenk : |
0.0 alert |
Leadlikeness : |
1.0 |
Synthetic accessibility : |
1.52 |