Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | ||||||
{[ item.p_purity ]} | {[ item.pr_size ]} | Inquiry |
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price) ]} |
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price) ]} | {[ item.pr_usastock ]} | in stock Inquiry - | {[ item.pr_chinastock ]} | {[ item.pr_remark ]} in stock Inquiry - | Login | Inquiry |
Please Login or Create an Account to: See VIP prices and availability
CAS No. : | 111-70-6 | MDL No. : | MFCD00002986 |
Formula : | C7H16O | Boiling Point : | - |
Linear Structure Formula : | CH3CH2CH2CH2CH2CH2CH2OH | InChI Key : | BBMCTIGTTCKYKF-UHFFFAOYSA-N |
M.W : | 116.20 | Pubchem ID : | 8129 |
Synonyms : |
n-Heptyl alcohol
|
Signal Word: | Warning | Class: | |
Precautionary Statements: | P210-P261-P264-P270-P271-P273-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501 | UN#: | |
Hazard Statements: | H227-H302+H312+H332-H319-H402 | Packing Group: | |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
(28-1) Synthesis of 4-heptyloxy-3-trifluoromethylbenzoic acid (compound 28-1) To a suspension of potassium t-butoxide (20.7 g) in N,N-dimethylformamide (120 ml) was added n-heptanol (15.6 ml), and the mixture was stirred at room temperature for 30 min. A solution of <strong>[67515-55-3]4-fluoro-3-trifluoromethylbenzoic acid</strong> (16.7 g) in N,N-dimethylformamide (60 ml) was added dropwise to the reaction mixture at 0C, and the mixture was stirred at 70C for 1 hr. The reaction mixture was ice-cooled, water (320 ml) was added, and 6M-hydrochloric acid (40 ml) was added at room temperature. The mixture was stirred at room temperature for 30 min and precipitated crystals were collected by filtration. The crystals were dissolved in ethanol (60 ml) at 70C, water (96 ml) was added dropwise at the same temperature and the mixture was stirred for 30 min. The mixture was allowed to cool to room temperature, and stirred for 30 min under ice-cooling. The precipitated crystals were collected by filtration to give the object product (24.1 g) as pale-brown crystals. 1H-NMR(CDCl3)delta(ppm): 0.90(3H, t, J=6.6Hz), 1.28-1.49(8H, m), 1.80-1.90(2H, m), 4.13(2H, t, J=6.3Hz), 7.04(1H, d, J=8.7Hz), 8.24(1H, dd, J=2.1Hz, 9.0Hz), 8.33(1H, d, J=1.8Hz). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
95% | With 1-Bromoheptane; at 150℃; for 48h;Green chemistry; | <strong>[4214-79-3]2-hydroxy-5-chloropyridine</strong> (0.259 g, 2 mmol), 1-heptanol (2.4 mmol,1.2 equiv.) And 1-bromoheptane (0.1257 ml, 40 molpercent)were added successively in a tubular reactor,Sealed under air and thenheated to 150 ° C for 48 hunder solvent-free conditions.After the TLC monitoring reaction was complete, the product was purified by column chromatography and the yield was 95percent. |