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[ CAS No. 105973-51-1 ] {[proInfo.proName]}

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Chemical Structure| 105973-51-1
Chemical Structure| 105973-51-1
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Product Details of [ 105973-51-1 ]

CAS No. :105973-51-1 MDL No. :MFCD00044200
Formula : C12H18ClNO Boiling Point : No data available
Linear Structure Formula :- InChI Key :PHJDPNCYJSWYGY-UHFFFAOYSA-N
M.W : 227.73 Pubchem ID :16218306
Synonyms :

Safety of [ 105973-51-1 ]

Signal Word:Warning Class:
Precautionary Statements:P280-P305+P351+P338 UN#:
Hazard Statements:H302 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 105973-51-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 105973-51-1 ]

[ 105973-51-1 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 75-44-5 ]
  • [ 105973-51-1 ]
  • [ 142930-13-0 ]
  • 2-Methoxy-4-methyl-6-(2-trifluoromethyl-phenyl)-6H-pyrimidine-1,5-dicarboxylic acid 1-(1-benzyl-piperidin-3-yl) ester 5-isopropyl ester [ No CAS ]
  • 3
  • [ 105973-51-1 ]
  • [ 71037-71-3 ]
  • [ 623581-31-7 ]
  • 4
  • [ 105973-51-1 ]
  • [ 623581-35-1 ]
  • 5
  • [ 105973-51-1 ]
  • [ 623581-36-2 ]
  • 6
  • [ 105973-51-1 ]
  • C22H24N4O2 [ No CAS ]
  • 7
  • [ 105973-51-1 ]
  • [ 623581-32-8 ]
  • 8
  • [ 105973-51-1 ]
  • C20H21N5O3 [ No CAS ]
  • 9
  • [ 105973-51-1 ]
  • 4-Methyl-2-oxo-6-(2-trifluoromethyl-phenyl)-3,6-dihydro-2H-pyrimidine-1,5-dicarboxylic acid 1-(1-benzyl-piperidin-3-yl) ester 5-isopropyl ester [ No CAS ]
  • 10
  • N-benzyl-3-(tert-butyldimethylsiloxy)piperidin [ No CAS ]
  • [ 105973-51-1 ]
YieldReaction ConditionsOperation in experiment
95% With hydrogenchloride; In dichloromethane; water; at 20.0℃; for 1.0h; add 1L of dichloromethane to the container one by one,N-benzyl-4-(tert-butyldimethylsiloxy)piperidine (260g, 0.85mol), at room temperature,Slowly pass in hydrogen chloride gas (124.1g, 3.4mol), after passing through, stir for 1h at room temperature, filter,The filter cake is dissolved in 0.5L of water. Dissolve potassium carbonate (117.3g, 0.85mol) in 0.5L water,Control the temperature at 510 and drop into the above solution, and stir for 1h after dropping.184 g of N-benzyl-4-hydroxypiperidine hydrochloride was obtained by filtration, which was a white solid with a molar yield of 95%.
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