天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Home Cart 0 Sign in  

[ CAS No. 103831-11-4 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 103831-11-4
Chemical Structure| 103831-11-4
Structure of 103831-11-4 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 103831-11-4 ]

Related Doc. of [ 103831-11-4 ]

Alternatived Products of [ 103831-11-4 ]
Product Citations

Product Details of [ 103831-11-4 ]

CAS No. :103831-11-4 MDL No. :MFCD00059018
Formula : C4H12Cl2N2 Boiling Point : No data available
Linear Structure Formula :- InChI Key :NJPNCMOUEXEGBL-UHFFFAOYSA-N
M.W : 159.06 Pubchem ID :16212596
Synonyms :

Calculated chemistry of [ 103831-11-4 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 8
Num. arom. heavy atoms : 0
Fraction Csp3 : 1.0
Num. rotatable bonds : 0
Num. H-bond acceptors : 2.0
Num. H-bond donors : 2.0
Molar Refractivity : 42.58
TPSA : 38.05 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : Yes
Log Kp (skin permeation) : -6.8 cm/s

Lipophilicity

Log Po/w (iLOGP) : 0.0
Log Po/w (XLOGP3) : 0.66
Log Po/w (WLOGP) : 0.53
Log Po/w (MLOGP) : 0.21
Log Po/w (SILICOS-IT) : 0.28
Consensus Log Po/w : 0.34

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 2.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -1.24
Solubility : 9.11 mg/ml ; 0.0573 mol/l
Class : Very soluble
Log S (Ali) : -1.04
Solubility : 14.7 mg/ml ; 0.0922 mol/l
Class : Very soluble
Log S (SILICOS-IT) : -0.34
Solubility : 71.9 mg/ml ; 0.452 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.45

Safety of [ 103831-11-4 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P305+P351+P338 UN#:
Hazard Statements:H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 103831-11-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 103831-11-4 ]

[ 103831-11-4 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 96568-07-9 ]
  • [ 103831-11-4 ]
  • [ 96568-17-1 ]
  • 2
  • [ 116163-18-9 ]
  • [ 103831-11-4 ]
  • [ 116163-46-3 ]
  • 3
  • [ 125290-83-7 ]
  • [ 103831-11-4 ]
  • 7-((S)-3-Amino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • 4
  • [ 103831-11-4 ]
  • [ 138668-30-1 ]
  • [ 138668-32-3 ]
  • 5
  • [ 103831-11-4 ]
  • 7-Chloro-1-ethyl-6-fluoro-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • 7-((S)-3-Amino-pyrrolidin-1-yl)-1-ethyl-6-fluoro-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • 6
  • [ 103831-11-4 ]
  • 7-Chloro-6-fluoro-1-(2-fluoro-1,1-dimethyl-ethyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • 7-((S)-3-Amino-pyrrolidin-1-yl)-6-fluoro-1-(2-fluoro-1,1-dimethyl-ethyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • 7
  • [ 103831-11-4 ]
  • 7-Chloro-6-fluoro-1-(2-fluoro-ethyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • 7-((S)-3-Amino-pyrrolidin-1-yl)-6-fluoro-1-(2-fluoro-ethyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • 8
  • [ 103831-11-4 ]
  • [ 132195-55-2 ]
  • [ 132195-56-3 ]
  • 9
  • [ 103831-11-4 ]
  • [ 138668-31-2 ]
  • 7-((S)-3-Amino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-5-phenyl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • 10
  • [ 103831-11-4 ]
  • 7-Chloro-6-fluoro-1-(4-fluoro-phenyl)-5-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester [ No CAS ]
  • [ 132195-48-3 ]
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 103831-11-4 ]

Amines

Chemical Structure| 116183-81-4

[ 116183-81-4 ]

(R)-Pyrrolidin-3-amine dihydrochloride

Similarity: 1.00

Chemical Structure| 116183-83-6

[ 116183-83-6 ]

(S)-Pyrrolidin-3-amine dihydrochloride

Similarity: 1.00

Chemical Structure| 116183-82-5

[ 116183-82-5 ]

(R)-Pyrrolidin-3-amine

Similarity: 0.95

Chemical Structure| 50534-42-4

[ 50534-42-4 ]

N,N-Dimethylpyrrolidin-3-amine dihydrochloride

Similarity: 0.88

Chemical Structure| 864448-61-3

[ 864448-61-3 ]

(R)-Dimethylpyrrolidin-3-yl-amine dihydrochloride

Similarity: 0.88

Related Parent Nucleus of
[ 103831-11-4 ]

Aliphatic Heterocycles

Chemical Structure| 116183-81-4

[ 116183-81-4 ]

(R)-Pyrrolidin-3-amine dihydrochloride

Similarity: 1.00

Chemical Structure| 116183-83-6

[ 116183-83-6 ]

(S)-Pyrrolidin-3-amine dihydrochloride

Similarity: 1.00

Chemical Structure| 116183-82-5

[ 116183-82-5 ]

(R)-Pyrrolidin-3-amine

Similarity: 0.95

Chemical Structure| 50534-42-4

[ 50534-42-4 ]

N,N-Dimethylpyrrolidin-3-amine dihydrochloride

Similarity: 0.88

Chemical Structure| 913702-34-8

[ 913702-34-8 ]

(R)-1,3'-Bipyrrolidine dihydrochloride

Similarity: 0.88

Pyrrolidines

Chemical Structure| 116183-81-4

[ 116183-81-4 ]

(R)-Pyrrolidin-3-amine dihydrochloride

Similarity: 1.00

Chemical Structure| 116183-83-6

[ 116183-83-6 ]

(S)-Pyrrolidin-3-amine dihydrochloride

Similarity: 1.00

Chemical Structure| 116183-82-5

[ 116183-82-5 ]

(R)-Pyrrolidin-3-amine

Similarity: 0.95

Chemical Structure| 50534-42-4

[ 50534-42-4 ]

N,N-Dimethylpyrrolidin-3-amine dihydrochloride

Similarity: 0.88

Chemical Structure| 913702-34-8

[ 913702-34-8 ]

(R)-1,3'-Bipyrrolidine dihydrochloride

Similarity: 0.88

; ;