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  W9013    AKSci Reference Standard
Crizotinib
, 99% (HPLC), powder
 
PF-02341066, (R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine




IDENTITY
CAS Number:877399-52-5
MDL Number:MFCD12407409
MF:C21H22Cl2FN5O
MW:450.34
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:197-203°C
Density:1.475
Refractive Index:1.673
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):c-Met and ALK inhibitor

REVIEW

 Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nnM, respectivley.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H317; H319; H341; H400

Precautionary Statements
P201; P202; P261; P264; P272; P273; P280; P281; P302+P352; P305+P351+P338; P308+P313; P333+P313; P337+P313; P363; P391; P405; P501


Current as of December 22, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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All batches backed with full quality assurance.
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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Protein Kinase Inhibitors


PubChem
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