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  J10151    AKSci Reference Standard
Cetirizine dihydrochloride
, >99% (HPLC), powder
 
Cetirizine
Reactine
Zyrtec
more..




IDENTITY
CAS Number:83881-52-1
MDL Number:MFCD00941428
MF:C21H27Cl3N2O3
MW:461.81
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:217-225°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 92mg/mL; H2O: >10mg/mL; EtOH: <1mg/mL
Application(s):Selective H1-receptor antagonist
Form:HCl salt

REVIEW

 An antihistamine. It is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria.

REFERENCES
[1]Espay AJ (2008). Reversible parkinsonism and ataxia associated with high-dose octreotide. Neurology. 70(24):2345-6. PMID 18463367.
[2] Jones MC, Jones CE 2nd (2010). Use of cetirizine in a 23-month-old male causes insomnia. South Med J. 103(5):485-6. PMID 20375960.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P264; P270; P301+P312; P330; P501


Current as of January 3, 2025

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Antihistamines


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