Sold as technical grade. Not an analytical standard. No purity specification available.
DOT/IATA TRANSPORT INFORMATION
Not hazardous material
BIOLOGICAL INFO
Application(s):
Carbonic Anhydrase Inhibitor
Form:
Free Base
REVIEW Punicalagin is an ellagitannin, a phenolic compounds, with a alpha and beta form, found in pomegranates. It is the most abundant polyphenol in pomegranetes, and accounts for >50% of the antioxidant activity. Punicalagin is widely used for the treatment of inflammatory bowel disease (IBD), diarrhea, and ulcers. Since it could inhibit lipopolysaccharide -induced inflammation, it may be a potential choice for the treatment of inflammation diseases.
REFERENCES
[1]
Tanaka, Takashi; Nonaka, Genichiro; Nishioka, Itsuo. Tannins and related compounds. XLI. Isolation and characterization of novel ellagitannins, punicacorteins A, B, C and D, and punigluconin from the bark of Punica granatum L. Chemical & Pharmaceutical Bulletin. (1986) 34(2): 656-63.
[2]
Lin C C; Hsu Y F; Lin T C; Hsu F L; Hsu H Y. Antioxidant and hepatoprotective activity of punicalagin and punicalin on carbon tetrachloride-induced liver damage in rats. The Journal of Pharmacy and Pharmacology. (1998) 50(7): 789-94.
[3]
Wang SG, Huang MH, Li JH, Lai FI, Lee HM, Hsu YN. Punicalagin induces apoptotic and autophagic cell death in human U87MG glioma cells. Acta Pharmacol Sin. (2013) Nov;34(11): 1411-9.
[4]
Lopez Mas, Jose A.; Streitenberger, Sergio, A.; Penalver Mellado, Marcos; Martinez Ortiz, Pedro Process and apparatus for preparing pomegranate extracts Eur. Pat. Appl. (2008), EP 1967078 A1 20080910.
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All batches backed with full quality assurance.
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